PMID: 375398May 1, 1979Paper

Renal tubular dysfunction in transplanted kidneys

Southern Medical Journal
N D VaziriD C Martin

Abstract

We studied 15 renal transplant recipients for evidence of tubular dysfunction. Eight patients were hypophosphatemic, and two had systemic acidosis with a urinary acidification defect. Mild aminoaciduria and bicarbonaturia were present in four and 14 patients, respectively. Elevated parathyroid hormone level was found in only one patient. Tubular reabsorption of phosphorus was depressed in all eight hypophosphatemic patients, while no such abnormalities were observed in 14 control subjects. Defective tubular reabsorption of phosphorus was the most striking abnormality. None of the parameters studied, including immunosuppressant therapy, parathyroid hormone levels, creatinine clearance, or acid-base balance, clearly account for the pathogenesis of this abnormality.

Citations

Sep 17, 1984·Klinische Wochenschrift·F C Reubi, A Montandon
Sep 1, 1989·Klinische Wochenschrift·W H HörlH Wilms
Jan 1, 1986·International Urology and Nephrology·L SzalayC W Gottschalk
Jan 1, 1984·International Urology and Nephrology·V RevúsováV Pribylincová
Mar 1, 1984·Environmental Health Perspectives·C G ElinderM Piscator
Apr 1, 1981·The American Journal of Medicine·D C BatlleN A Kurtzman
Apr 20, 2000·Journal of the American Society of Nephrology : JASN·David M Clive

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