Renal vein thrombosis associated with oral contraception and smoking: a case report from Japan, with literature review

CEN Case Reports
Yosuke SasakiHiroyasu Yonaha

Abstract

Renal vein thrombosis, one of the common thrombotic complications of nephrotic syndrome or renal cell carcinoma, is reportedly a rare complication of hormonal contraception. Solitary renal vein thrombosis in the Japanese population is thought to be very rare because the incidence of venous thromboembolism is comparatively very low in Asian populations. We report a 38-year-old Japanese female with left renal vein thrombosis associated with oral contraception and concurrent smoking as the first Japanese case of solitary renal vein thrombosis associated with oral contraceptives, with a review of the literature. Seven cases were previously reported. The results revealed that all patients complained of acute onset of pain around the involved kidney without urinary symptoms or fever, and were effectively treated with anticoagulants. Other remarkable facts include that nausea and vomiting were frequently seen, and that the renal outcome was benign, despite various initial urine abnormalities. This report may alert clinicians to the importance of these risk factors as an etiology of renal vein thrombosis even in Asian populations. Clinicians should regard renal vein thrombosis as one of the differential diagnoses for acute flank pain i...Continue Reading

References

Jul 1, 1990·American Journal of Obstetrics and Gynecology·J L DavidM R Lepot
Jan 1, 1989·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J BöhlerP Schollmeyer
Jan 1, 1983·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R S GoldmanT A Borden
Feb 26, 1997·JAMA : the Journal of the American Medical Association·S Z GoldhaberC H Hennekens
Jun 2, 2006·Obstetrics and Gynecology·UNKNOWN ACOG Committee on Practice Bulletins-Gynecology
Oct 18, 2007·Current Opinion in Pulmonary Medicine·Craig R Keenan, Richard H White
Jun 13, 2009·Thrombosis Research·Richard H White, Craig R Keenan
Aug 15, 2009·BMJ : British Medical Journal·Øjvind LidegaardCarsten Agger
Mar 17, 2010·The American Journal of the Medical Sciences·Akash AjmeraLawrence Weisberg

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Citations

Oct 23, 2018·The American Journal of Forensic Medicine and Pathology·Roger W Byard
Apr 10, 2019·The Journal of Clinical Pediatric Dentistry·Arturo Garrocho-RangelAmaury Pozos-Guillén

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