PMID: 7018406Apr 1, 1981Paper

Renin and angiotensin levels in children

Archives of Disease in Childhood
F Broughton PipkinM O'Callaghan

Abstract

Plasma renin activity, plasma renin concentration, and angiotensin II levels were measured in 63 normal children aged between 2 months and 12 years. The results showed that the high levels of renin and angiotensin II present in infancy remained above adult levels throughout the first decade of life but that there was a decline with age. Boys less than 8 years old had lower plasma renin activity and angiotensin II levels than girls of a similar age; this may be due to a relative substrate deficiency. Serum urea levels were inversely correlated with plasma renin activity in both sexes. A significant inverse relationship was found between both plasma renin activity and angiotensin II, and serum sodium in the girls; a similar, although not statistically significant, relationship was seen with plasma renin activity in the boys. An inverse correlation was found between plasma renin concentration and diastolic blood pressure for the group as a whole.

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Citations

Jul 27, 2011·Plastic and Reconstructive Surgery·Tinte ItinteangSwee Thong Tan
Apr 6, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·M MiyawakiN Yoshikawa
Apr 1, 1984·Archives of Disease in Childhood·K D GriffithsP H Rayner
Apr 25, 2012·Journal of the Renin-angiotensin-aldosterone System : JRAAS·Juan GaoLie Gao
Dec 1, 1983·Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie·K J Van AckerA K Amery
Oct 1, 1989·European Journal of Pediatrics·K ShimomuraK Ueda
Jan 1, 1984·Clinical and Experimental Hypertension. Part A, Theory and Practice·S GotiaI Haulica
Jan 15, 2016·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Bjoern B BurckhardtStephanie Läer
Jul 10, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Swee T TanPhilip Leadbitter
Mar 5, 2016·Archives of Dermatological Research·Sophie de JongSwee T Tan
Aug 14, 2012·Pediatric Annals·Lily Changchien UihleinJohn B Mulliken
Mar 11, 2008·Early Human Development·Masakazu MiyawakiNorishige Yoshikawa
Feb 14, 2012·Paediatric and Perinatal Epidemiology·Marije J HoornwegChantal M A M van der Horst
Feb 27, 2013·Journal of the Renin-angiotensin-aldosterone System : JRAAS·Shane D SykesUNKNOWN SCOPE Consortium
Apr 13, 2017·Birth Defects Research·Chelsey J Forbess SmithChristina D Chambers
May 31, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Nicholas J A WebbRobert O Blaustein
Oct 23, 2015·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Yu-Juan TangLie Wang
Jul 15, 2020·Expert Review of Clinical Pharmacology·Sabrina P KohSwee T Tan
Jan 1, 1983·Acta Medica Scandinavica. Supplementum·P Skøtt, J Giese
Jan 7, 2021·American Journal of Physiology. Lung Cellular and Molecular Physiology·Zaid AbassiSamuel N Heyman

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