Renoprotective Mono- and Triterpenoids from the Fruit of Gardenia jasminoides.

Journal of Natural Products
Yan-Gang CaoWei-Sheng Feng

Abstract

This paper describes the isolation and characterization of 17 new and 12 known terpenoids from the fruit of Gardenia jasminoides. The structures of eight new triterpenoids and nine new monoterpenoids, including their absolute configurations, were defined by spectroscopic analysis in combination of quantum chemical electronic circular dichroism (ECD), vibrational circular dichroism (VCD), and gauge-independent atomic orbital (GIAO) NMR calculations. The cytoprotective effects of the isolated compounds against lipopolysaccharide (LPS)-induced apoptosis in normal rat kidney tubule epithelioid (NRK 52e) cells were investigated in vitro. Compounds 10, 18, 20, 21, 24, and 26 exhibited significant protective effects with EC50 values from 14.2 nM to 1.6 μM.

References

Mar 27, 2004·Journal of Natural Products·Ayumi OhsakiJunko Takashima
Sep 28, 2006·Clinical and Experimental Pharmacology & Physiology·Sei-Jung LeeKye-Taek Lim
Dec 28, 2006·Journal of Natural Products·Raphaël GrougnetSylvie Michel
May 29, 2008·Journal of Natural Products·Quan Cheng ChenKiHwan Bae
Apr 17, 2009·Phytochemistry·Quan Cheng ChenKiHwan Bae
May 8, 2009·Chemical & Pharmaceutical Bulletin·Guang ChenJi-Ming Jia
Jan 16, 2010·Phytochemistry·Yanpeng HouDavid G I Kingston
Sep 30, 2010·Journal of Natural Products·Jing-Jy ChengYao-Haur Kuo
Feb 3, 2012·Journal of Asian Natural Products Research·Jia-Yi TaoKe Liu
Sep 8, 2012·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S KustermannA Roth
Oct 27, 2012·Fitoterapia·Khalijah AwangKhalit Mohamad
Jan 29, 2013·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Bidya Dhar SahuRamakrishna Sistla
Apr 10, 2013·Fitoterapia·Hai-Bo LiXin-Sheng Yao
Oct 1, 2013·Chemistry & Biodiversity·Sreekanth GandheOlaf Kunert
Oct 4, 2013·Chemical & Pharmaceutical Bulletin·Fang-Min QinGuang-Xiong Zhou
Nov 27, 2014·Natural Product Research·Fang-Min QinGuang-Xiong Zhou
Feb 7, 2015·Natural Product Research·Shaofu YuGuangxiong Zhou
Nov 27, 2015·Phytochemistry·Hoang Linh MaiRaphaël Grougnet
Dec 15, 2015·British Journal of Pharmacology·Hong-Ik ChoSun-Mee Lee
Dec 30, 2016·Journal of Natural Products·Xing-Wei YangGang Xu

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Citations

Feb 22, 2021·Carbohydrate Research·Penghua ShuWenhan Yi
Aug 1, 2021·Phytochemistry·Yan-Gang CaoWei-Sheng Feng
Aug 28, 2021·Natural Product Research·Mengnan ZengWeisheng Feng

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Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

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