Renovation of the injured heart with myocardial tissue engineering

Expert Review of Cardiovascular Therapy
Jonathan LeorSmadar Cohen

Abstract

Tissue engineering aims to create, repair and/or replace tissues and organs by using cells, scaffolds, biologically active molecules and physiologic signals. It is an interdisciplinary field that integrates aspects of engineering, chemistry, biology and medicine. One of the most challenging goals in the field of cardiovascular tissue engineering is the creation of a heart muscle patch. This review describes the principles, achievements and challenges of achieving this ambitious goal of creating contractile heart muscle. In addition, the new strategy of in situ and injectable tissue engineering for myocardial repair and regeneration is presented.

References

Jul 1, 1995·Cell Transplantation·C K Colton
Jul 1, 1997·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·T EschenhagenE L Elson
Nov 6, 1998·Science·J A ThomsonJ M Jones
Dec 22, 1998·Journal of Biomaterials Science. Polymer Edition·M C PetersD J Mooney
Jan 23, 1999·Biomaterials·J A RowleyD J Mooney
Jul 15, 1999·Biotechnology and Bioengineering·R L CarrierG Vunjak-Novakovic
Oct 12, 1999·Circulation·D L Eckberg
Jan 29, 2000·The Journal of Thoracic and Cardiovascular Surgery·R K LiZ Q Jia
Mar 4, 2000·Biotechnology and Bioengineering·W H ZimmermannT Eschenhagen
Apr 1, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·C FinkT Eschenhagen
Dec 21, 2000·American Journal of Physiology. Heart and Circulatory Physiology·M PapadakiL E Freed
Mar 16, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·A S. KrupnickB R. Rosengard
May 10, 2001·Journal of Molecular and Cellular Cardiology·M ZhangC E Murry
Jul 20, 2001·Annals of the New York Academy of Sciences·V W van HinsberghP Koolwijk
Nov 2, 2001·Nature Biotechnology·T P RichardsonD J Mooney
Feb 9, 2002·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Alexander S KrupnickBruce R Rosengard
Feb 9, 2002·Circulation Research·W-H ZimmermannT Eschenhagen
Feb 9, 2002·Science·Larry L Hench, Julia M Polak
Feb 9, 2002·Journal of Biomedical Materials Research·Tatsuya ShimizuTeruo Okano
Mar 29, 2002·Journal of Biomedical Materials Research·Todd C McDevittPatrick S Stayton
Apr 12, 2002·Journal of Molecular and Cellular Cardiology·Hans Reinecke, Charles E Murry
May 29, 2002·Tissue Engineering·Rebecca L CarrierGordana Vunjak-Novakovic
Jun 1, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Alok TiwariAlexander M Seifalian
Jun 25, 2002·Asian Cardiovascular & Thoracic Annals·Pascal M DohmenWolfgang F Konertz
Jul 2, 2002·The Journal of Thoracic and Cardiovascular Surgery·T KofidisA Haverich
Aug 30, 2002·Basic Research in Cardiology·Yao SunKarl T Weber
Sep 13, 2002·Biotechnology and Bioengineering·Ayelet DarSmadar Cohen
Dec 3, 2002·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Elena Rabkin, Frederick J Schoen
Jan 9, 2003·Lancet·Christof StammGustav Steinhoff
Feb 28, 2003·Nature·Catherine Zandonella

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Citations

Nov 21, 2008·Journal of Materials Science. Materials in Medicine·Yanxia ZhuZhanfeng Cui
Aug 1, 2009·Tissue Engineering. Part a·Ayelet LesmanLior Gepstein
Feb 15, 2012·Annals of Surgery·Giuseppe OrlandoShay Soker
Jul 1, 2007·Future Cardiology·Wolfram-Hubertus ZimmermannThomas Eschenhagen
Nov 7, 2013·Expert Opinion on Biological Therapy·Sabri MusaNoor Hayaty Abu Kasim
Jan 15, 2016·Tissue Engineering. Part a·Andrea StoehrThomas Eschenhagen
Jul 30, 2014·Journal of Tissue Engineering and Regenerative Medicine·Lewis A ReisMilica Radisic
Feb 1, 2011·Advanced Drug Delivery Reviews·C V C BoutenF P T Baaijens
Jan 15, 2014·Biomacromolecules·Ana M MartinsGordana Vunjak-Novakovic
Feb 23, 2008·The Annals of Thoracic Surgery·Juan C ChachquesAlain Carpentier
May 8, 2018·Advanced Healthcare Materials·Jesus Paez-MayorgaAli Khademhosseini
May 31, 2008·Expert Review of Cardiovascular Therapy·Emil RuvinovSmadar Cohen
Aug 21, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yuan-Kun Aden Wu, Jiashing Yu
Mar 16, 2021·Frontiers in Cardiovascular Medicine·Lu WangJianyi Zhang

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