PMID: 16633179Apr 25, 2006Paper

Repair of bone defects treated with autogenous bone graft and low-power laser

The Journal of Craniofacial Surgery
Rosane Vierra da Silva, José Angelo Camilli

Abstract

Because bone healing at the graft site is similar to a fracture repair, the purpose of the present study was to evaluate the effects of low-power laser irradiation on the repair of rat skull defects treated with autogenous bone graft. A defect measuring 3 mm in diameter was produced in the left parietal bone and filled with an autogenous bone graft obtained from the right parietal bone. The animals were divided into 3 groups of 20 rats each: nonirradiated control, irradiated with 5.1 J/cm, and irradiated with 10.2 J/cm. The laser (2.4 mW, 735 nm, 3.4 x 10 W/cm, 3-mm spot size) was applied three times per week for 4 weeks. Greater volume of newly formed bone was observed in the irradiated group with 10.2 J/cm. In both irradiated groups, a greater volume of newly formed bone occurred only in the first 2 weeks. The results demonstrated that laser irradiation at the grafted site stimulated osteogenesis during the initial stages of the healing process in a skull defect of the rat and that this effect was dose dependent.

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Citations

Mar 1, 2008·Lasers in Medical Science·Mariza A MatsumotoDaniel A Ribeiro
Oct 29, 2009·Photomedicine and Laser Surgery·Utkan Kamil Akyol, Metin Güngörmüş
Jul 2, 2014·BioMed Research International·Mércia J S CunhaAna Lúcia P F de Almeida
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