Repeat sentinel lymph node procedure in patients with recurrent vulvar squamous cell carcinoma is feasible

Gynecologic Oncology
Helena C van DoornJohanna A de Hullu

Abstract

Standard treatment of primary T1 squamous cell carcinoma (SCC) of the vulva <4cm consists of wide local excision (WLE) and sentinel lymph node (SLN) procedure of the groin(s). In case of a local recurrence WLE and inguino femoral lymphadenectomy (IFL) is generally recommended. In this study we assessed the feasibility of repeat SLN procedure in patients with recurrent vulvar SCC who were not able or willing to undergo IFL. A retrospective study was performed in consecutive patients with recurrent vulvar SCC who underwent a repeat SLN procedure between 2006 and 2014. We present the clinical and pathological outcomes. The study conforms to the STROBE guidelines. A total number of 27 patients aged 35-87years at first diagnosis of SCC of the vulva were identified. Median follow-up after 2nd surgery was 27.4 (range 2-96) months. In 78% of patients and in 84% of the groins the repeat SLN procedure was successful. No structured questionnaires were used to describe details on the repeat SLN procedures but in general the gynecologic oncologists experienced repeat SLN procedures more challenging compared to primary procedures. There were no groin recurrences documented. Our findings suggest that it is feasible to perform a repeat SLN pro...Continue Reading

References

Jul 27, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·J A de HulluA G van der Zee
Jan 31, 2004·Gynecologic Oncology·Michael FrumovitzCharles Levenback
Sep 19, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·A P LandkroonA C Ansink
Feb 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ate G J Van der ZeeWim J Sluiter
Oct 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Tessa A EnnikPeter T Grant
Jan 21, 2012·TheScientificWorldJournal·A A SolimanP Wimberger
Jul 4, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles F LevenbackCornelia L Trimble
Jan 24, 2013·Breast Cancer Research and Treatment·Adriana J G Maaskant-BraatGrard A P Nieuwenhuijzen
Feb 20, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·B E SchaafsmaK N Gaarenstroom
Feb 18, 2014·Journal of the American College of Surgeons·Georgia M BeasleyDouglas S Tyler
Mar 19, 2014·Gynecologic Oncology·Katina RobisonRichard G Moore
Apr 24, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Wiebren Age Andries Tjalma
Aug 16, 2014·Gynecologic Oncology·Henricus J M HandgraafKatja N Gaarenstroom
Oct 24, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Maaike H M OonkAte J G van der Zee
Nov 22, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Marta NovackovaLukas Rob

❮ Previous
Next ❯

Citations

Sep 18, 2016·Critical Reviews in Oncology/hematology·L S NooijM I E van Poelgeest
Jun 14, 2017·Expert Review of Anticancer Therapy·Anne-Floor W PouwerJoanne A de Hullu
Dec 5, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Diana ZachPreben Kjölhede
Jan 4, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Angela CollarinoMarco Maccauro
Sep 23, 2020·Radiology and Oncology·Sebastjan Merlo
Apr 28, 2020·Gynécologie, Obstétrique, Fertilité & Sénologie·E SerreUNKNOWN Groupe de Recherche FRANCOGYN
Oct 7, 2019·Bulletin du cancer·Denis QuerleuFrançois Planchamp

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Heleen J van BeekhuizenHelena C van Doorn
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
B Cady
© 2022 Meta ULC. All rights reserved