Repeat two-stage exchange arthroplasty for prosthetic hip re-infection

The Bone & Joint Journal
T S BrownM P Abdel

Abstract

Recurrent infection following two-stage revision total hip arthroplasty (THA) for prosthetic joint infection (PJI) is a devastating complication. The purpose of this study was to report the survival of repeat two-stage revision hip arthroplasty, describe complications, and identify risk factors for failure. We retrospectively identified 19 hips (19 patients) that had undergone repeat two-stage revision THA for infection between 2000 to 2013. There were seven female patients (37%) and the mean age was 60 years (30 to 85). Survival free from revision was assessed via Kaplan-Meier analysis. The patients were classified according to the Musculoskeletal Infection Society (MSIS) system, and risk factors for failure were identified. Mean follow-up was four years (2 to 11). Gram-positive bacteria were responsible for 16/17 (94%) of the re-infections where microbes were identified. Following the repeat two-stage exchange arthroplasty, survival free from any revision was 74% (95% confidence interval (CI) 56% to 96%, 14 at risk) at two years and 45% (95% CI 25% to 75%, five at risk) at five years. Failure to control infection resulted in re-operation or revision in 42%A of patients (8/19). Survival free from revision was not dependent on ...Continue Reading

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Citations

Jul 19, 2019·The Journal of Bone and Joint Surgery. American Volume·Thomas K FehringAaron Tande
Jan 25, 2020·Clinical Orthopaedics and Related Research·Adam Coughlan, Fraser Taylor
Sep 8, 2020·The Journal of Arthroplasty·Christoph TheilBurkhard Moellenbeck
Feb 21, 2021·The Journal of Arthroplasty·Bernhard J H FrankJochen G Hofstaetter
May 3, 2021·The Journal of Arthroplasty·Louis DagneauxMatthew P Abdel
Aug 12, 2021·Journal of Bone and Joint Infection·Katherine LiBryan D Springer
Jan 1, 2022·The Bone & Joint Journal·Emanuel F LiechtiMustafa Citak

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