PMID: 16633227Apr 25, 2006Paper

Repeatability of normal multifocal VEP: implications for detecting progression

Journal of Glaucoma
Brad FortuneChris A Johnson

Abstract

To assess the repeatability of the multifocal visual evoked potential (mfVEP) and to compare it with the repeatability of standard automated perimetry (SAP) in the same group of 50 normal controls retested after 1 year. Our second aim was to assess the repeatability of false alarm rates determined previously for the mfVEP using various cluster criteria. Fifty individuals with normal vision participated in this study (33 females and 17 males). The age range was 26.7 to 77.9 years and the group average age (+/- SD) was 51.4 (+/- 12.1) years. Pattern-reversal mfVEPs were obtained using a dartboard stimulus pattern in VERIS and two 8-minute runs per eye were averaged. The average number of days between the first and second mfVEP tests was 378 (+/- 58). SAP visual fields were obtained within 17.4 (+/- 20.3) days of the mfVEP using the SITA-standard threshold algorithm. Repeatability of mfVEPs and SAP total deviation values were evaluated by calculating point-wise limits of agreement (LOA). Specificity (1-false alarm rate) was evaluated for a range of cluster criteria, whereby the number and probability level of the points defining a cluster were varied. Point-wise LOA for the mfVEP signal-to-noise ratio (SNR) ranged from 2.0 to 4.3 ...Continue Reading

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Citations

Oct 3, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·Boonchai WangsupadilokDonald C Hood
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Jan 1, 2021·Documenta Ophthalmologica. Advances in Ophthalmology·Paraskevas ZafeiropoulosIoannis Asproudis

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