Repeatability of Spectral Domain Optical Coherence Tomography Measurements in High Myopia

Journal of Glaucoma
Harsha L RaoBodduluri Lakshmi

Abstract

The purpose of this study was to compare the repeatability of spectral domain optical coherence tomography (SDOCT) parameters in high-myopic and emmetropic healthy subjects, and to evaluate the influence of axial length on the repeatability of SDOCT parameters in high myopia. In a prospective study, 93 eyes of 63 high-myopic subjects (spherical refractive error, -6 to -12 D; median age, 25 y) and 28 eyes of 14 emmetropic (spherical refractive error, 0 D; median age, 30 y) subjects underwent optic nerve head, retinal nerve fiber layer (RNFL), and ganglion cell complex imaging with SDOCT. For the repeatability analysis, 31 eyes of 31 high-myopic subjects and 14 eyes of 14 emmetropic subjects underwent 3 repeated scans in the same session. Among the optic nerve head parameters, within-subject coefficient of variation (CVw) measurements of the disc area (0.6% vs. 0.2%), rim area (8.7 vs. 2.8), and rim volume (16.7 vs. 8.9) were significantly larger (worse) in high-myopic compared with the emmetropic subjects. CVw measurements of all RNFL (range, 1.7 to 22.4) and ganglion cell complex (range, 1.8 to 2.5) parameters in high-myopic subjects were comparable to that in emmetropic subjects (2.4 to 24.0 and 1.7 to 2.0, respectively). Axia...Continue Reading

References

Mar 1, 1992·Archives of Ophthalmology·R J Glynn, B Rosner
Jul 13, 1996·BMJ : British Medical Journal·J M Bland, D G Altman
Sep 21, 1996·BMJ : British Medical Journal·J M Bland, D G Altman
Nov 14, 1997·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J B Jonas, A Dichtl
Apr 14, 2004·Archives of Ophthalmology·John H KempenUNKNOWN Eye Diseases Prevalence Research Group
Mar 1, 2005·American Journal of Ophthalmology·Eugene TayTin Aung
Mar 20, 2010·Investigative Ophthalmology & Visual Science·Shin Hee KangMyung Douk Ahn
Nov 6, 2010·Investigative Ophthalmology & Visual Science·Takuhei ShojiEtsuo Chihara
Feb 26, 2011·The British Journal of Ophthalmology·Giacomo SaviniMichele Carbonelli
Jun 21, 2011·Ophthalmology·Michael W MarcusNomdo M Jansonius
Oct 8, 2011·Ophthalmology·Tae-Woo KimJeong-Min Hwang
Jan 24, 2012·Investigative Ophthalmology & Visual Science·Harsha L RaoChandra S Garudadri
Sep 22, 2012·Investigative Ophthalmology & Visual Science·Christopher Kai-Shun LeungDennis Shun-Chiu Lam
Mar 21, 2013·Investigative Ophthalmology & Visual Science·Chen-Wei PanSeang-Mei Saw
Mar 13, 2014·Clinical & Experimental Ophthalmology·Yoshiyuki KitaIvan Goldberg

❮ Previous
Next ❯

Software Mentioned

RTVue
Stata
SDOCT

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.