Repeated binge ethanol administration during adolescence enhances voluntary sweetened ethanol intake in young adulthood in male and female rats.

Pharmacology, Biochemistry, and Behavior
Antoniette M Maldonado-DevincciCheryl L Kirstein

Abstract

Binge alcohol consumption is a rising concern in the United States, especially among adolescents. During this developmental period alcohol use is usually initiated and has been shown to cause detrimental effects on brain structure and function as well as cognitive/behavioral impairments in rats. Binge models, where animals are repeatedly administered high doses of ethanol typically over a period of three or four days cause these effects. There has been little work conducted aimed at investigating the long-term behavioral consequences of repeated binge administration during adolescence on later ethanol-induced behavior in young adulthood and adulthood. The repeated four-day binge model may serve as a good approximate for patterns of human adolescent alcohol consumption as this is similar to a "bender" in human alcoholics. The present set of experiments examined the dose-response and sex-related differences induced by repeated binge ethanol administration during adolescence on sweetened ethanol (Experiment 1) or saccharin (Experiment 2) intake in young adulthood. In both experiments, on postnatal days (PND) 28-31, PND 35-38 and PND 42-45, ethanol (1.5, 3.0 or 5.0 g/kg) or water was administered intragastrically to adolescent rats...Continue Reading

References

Sep 1, 1992·Alcohol·F E Lancaster, K S Spiegel
Dec 1, 1992·British Journal of Addiction·D S Hasin, H Glick
May 1, 1992·Alcohol·B A Gosnell, D D Krahn
Jul 1, 1981·Pharmacology, Biochemistry, and Behavior·J B HutchinsJ R Wilson
Jul 1, 1995·American Journal of Public Health·H WechslerS Castillo
Dec 7, 1994·JAMA : the Journal of the American Medical Association·H WechslerS Castillo
Oct 1, 1993·Alcoholism, Clinical and Experimental Research·B A BlanchardS D Glick
Apr 1, 1993·Alcoholism, Clinical and Experimental Research·J S GavalerM J Allan
Sep 1, 1996·Alcoholism, Clinical and Experimental Research·F E LancasterS B Wren
Oct 6, 1997·Alcoholism, Clinical and Experimental Research·C J Slawecki, H H Samson
May 15, 1998·Alcoholism, Clinical and Experimental Research·B J MarkwieseH S Swartzwelder
Jun 11, 1998·Alcoholism, Clinical and Experimental Research·M M Silveri, L P Spear
Jun 24, 1998·The Journal of Clinical Investigation·O F AlmeidaV K Patchev
Oct 1, 1998·Journal of General Internal Medicine·K A BradleyB Anawalt
Nov 5, 1998·Alcoholism, Clinical and Experimental Research·A J RobertsG F Koob
Jul 11, 2000·Alcoholism, Clinical and Experimental Research·K G HillR F Catalano
Dec 5, 2000·Alcoholism, Clinical and Experimental Research·F T CrewsD J Knapp
Aug 29, 2001·Alcohol·S PenlandF T Crews
Jan 5, 2002·Journal of Substance Abuse·B F GrantT C Harford
Jun 5, 2002·Alcoholism, Clinical and Experimental Research·Matthew M FordHerman H Samson
Nov 20, 2002·Journal of Neurochemistry·Kimberly Nixon, Fulton T Crews
Mar 28, 2003·Brazilian Journal of Biology = Revista Brasleira De Biologia·F K MarcondesA P Tanno
Oct 24, 2003·Alcoholism, Clinical and Experimental Research·Janelle M SilversDouglas B Matthews
Jan 28, 2004·Alcoholism, Clinical and Experimental Research·Elena I Varlinskaya, Linda P Spear
Sep 3, 2004·Pediatrics·Carolyn A McCartyFrederick P Rivara
Sep 15, 2004·Alcoholism, Clinical and Experimental Research·Alexey B Kampov-PolevoyF T Crews
Feb 17, 2005·Alcoholism, Clinical and Experimental Research·Peter M MontiFulton T Crews
Jul 28, 2005·Alcoholism, Clinical and Experimental Research·Sören SiegmundRainer Spanagel
Nov 5, 2005·Alcoholism, Clinical and Experimental Research·Tamara L DoremusLinda P Spear
Nov 18, 2005·Neuroscience·F T CrewsK Nixon
Jan 26, 2006·Alcoholism, Clinical and Experimental Research·Young May ChaH Scott Swartzwelder
Jul 18, 2006·Eating Behaviors·Alexey B Kampov-PolevoyJames C Garbutt
Sep 2, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Thomas C VaryAndrew Sumner
May 22, 2007·Alcoholism, Clinical and Experimental Research·Courtney S VetterLinda P Spear

❮ Previous
Next ❯

Citations

Dec 10, 2013·Psychopharmacology·Caroline QuoilinEtienne Quertemont
May 14, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Justin T GassL Judson Chandler
Jan 17, 2016·Pharmacological Reviews·Jill B Becker, George F Koob
Jan 10, 2012·Behavioural Brain Research·Caroline QuoilinEtienne Quertemont
Jan 2, 2016·Pharmacological Reviews·Styliani GoulopoulouR Clinton Webb
Sep 17, 2013·Alcoholism, Clinical and Experimental Research·Cynthia J M KanePaul D Drew
Jun 25, 2013·Pharmacology, Biochemistry, and Behavior·Jose Manuel Lerma-CabreraInmaculada Cubero
Jan 18, 2011·Pharmacology, Biochemistry, and Behavior·Pamela MettenJohn C Crabbe
Dec 17, 2014·BMC Gastroenterology·Elin SandBodil Ohlsson
Apr 27, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Jenny MoletLaurence Lanfumey
Sep 22, 2012·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Verica Milivojevic, Jonathan Covault
Aug 9, 2016·Pharmacology, Biochemistry, and Behavior·Brittany M PriddyLeandro F Vendruscolo
Sep 30, 2016·Pharmacological Reviews·Fulton T CrewsDonita L Robinson
Oct 18, 2018·Oxidative Medicine and Cellular Longevity·Luanna Melo Pereira FernandesCristiane Socorro Ferraz Maia
Apr 17, 2020·Frontiers in Behavioral Neuroscience·Trevor T Towner, Elena I Varlinskaya
Mar 20, 2019·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Hannah D FulenwiderJesse R Schank
Jul 19, 2020·Neuroscience and Biobehavioral Reviews·Craig D C BaileyCheryl M McCormick
Sep 1, 2021·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Ekaterina MugantsevaAntti Latvala

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Polyendocrinopathies

Autoimmune polyendocrinopathies, also called polyglandular autoimmune syndromes (PGASs), or polyendocrine autoimmune syndromes(PASs), are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. Discover the latest research on autoimmune polyendocrinopathies here.

Autoimmune Polyendocrine Syndromes

This feed focuses on a rare genetic condition called Autoimmune Polyendocrine Syndromes, which are characterized by autoantibodies against multiple endocrine organs. This can lead to Type I Diabetes.