Abstract
Adrenal cortical carcinoma (ACC) is a very rare type of tumor that generally has a poor prognosis. Little has been reported on repeated liver resections with recurrent metastasis still confined to the liver. In this report, we describe a case of functioning ACC in a 65-year-old woman with 2 liver metastases of the ACC (at 1.5 and 4 years) after the right adrenalectomy. A 65-year-old woman was referred to our hospital based on a suspicion of hyperaldosteronism. Abdominal computed tomography revealed a lesion at the right adrenal gland; therefore, we performed right adrenalectomy and subsequently diagnosed the lesion as ACC. However, follow-up computed tomography at 1.5 and 4 years after the right adrenalectomy revealed liver metastasis of ACC; liver resection was performed for both metastases. Complete surgical resection is the established approach for the treatment of ACC. The prognosis of ACC is usually dismal, and recurrence rates of up to 85% have been reported. However, the appropriate treatment for recurrent ACC is not well established, and the effectiveness of other modalities, such as chemotherapy and radiotherapy, is not proven. Therefore, surgical resection may currently be the most appropriate treatment modality, as t...Continue Reading
References
Mar 1, 1996·Clinical Endocrinology·M A CuestaJ C van Mourik
Sep 27, 2001·World Journal of Surgery·P IcardC Proye
Feb 15, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alexander StojadinovicMurray F Brennan
Mar 5, 2003·Annals of Internal Medicine·Melvin M GrumbachH Samuel Wieand
May 4, 2006·The Journal of Clinical Endocrinology and Metabolism·Gwenaelle AbivenJérôme Bertherat
Oct 26, 2006·The Journal of Clinical Endocrinology and Metabolism·Guillaume AssiéEric Baudin
Apr 30, 2009·Cancer·Buelent PolatMichael Flentje
Jul 4, 2009·Clinical Medicine & Research·Sreelatha ChalasaniAlan K McKenzie
Aug 12, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Irina VeytsmanTito Fojo
Oct 20, 2009·The Surgical Clinics of North America·Melissa WandoloskiMichael J Demeure
Oct 24, 2009·Annals of Surgical Oncology·Elizabeth G GrubbsJeffrey E Lee
Dec 23, 2011·Journal of Surgical Oncology·Nicole M DatriceItzhak Avital
Apr 25, 2012·Annals of Surgical Oncology·Sébastien GaujouxWilliam R Jarnagin
Nov 15, 2012·The Journal of Clinical Endocrinology and Metabolism·Ilknur ErdoganUNKNOWN German Adrenocortical Carcinoma Study Group