PMID: 9555561Apr 29, 1998Paper

Repeated urine analysis in patients with calcium stone disease

European Urology
H Bek-Jensen, H G Tiselius

Abstract

To study the variability in urine composition with respect to factors of importance for the calcium salt crystallization process and to test the reliability of using one or several urine samples in the clinical evaluation. Twelve patients collected 16-hour daytime and 8-hour night urine samples during 4 days of the same week. The urine was analysed for calcium, oxalate, phosphate, magnesium, citrate and pH, and the ion activity products of CaOx [AP(CaOx) index] and CaP were calculated. The risk of CaOx crystallization, as well as the inhibition of CaOx crystal growth and aggregation, were assessed. There was a good correlation between estimates of the AP(CaOx) index in the different samples, as well as between the AP(CaOx) index and the direct assessment of the risk of CaOx crystallization in the night and daytime urine samples. There was, however, a pronounced intra-individual variation of all variables and parameters. With the assumption that an abnormality would appear in at least one of the four samples, we found that in more than 80% of the cases, two 24-hour (16 + 8 h) urine samples were sufficient to establish whether the patient had a normal or an abnormal urine composition. Urine samples collected during two 24-, 16- o...Continue Reading

Citations

Feb 15, 2001·The Journal of Urology·C Y PakJ R Poindexter
Aug 25, 1999·Current Opinion in Urology·A W Krautschick
Oct 16, 2009·Urological Research·Y M Fazil Marickar, Abiya Salim
Apr 28, 2006·Urological Research·Hans-Göran Tiselius
Mar 19, 2014·Clinical Chemistry and Laboratory Medicine : CCLM·Guohua ZengJian Yuan
Jun 15, 2013·The Journal of Urology·Daniel M MoreiraZeph Okeke
Sep 27, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Daniel M MoreiraZeph Okeke
Apr 15, 2006·Urological Research·Sefa ResimMetin Kilinc
Sep 26, 2007·Urologia Internationalis·Domenico PreziosoGennaro Iapicca
Apr 24, 2003·BJU International·H-G Tiselius
Feb 24, 2001·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·R SelvamA S Sathish Kumar
Dec 12, 2002·Endocrinology and Metabolism Clinics of North America·Hans-Göran Tiselius

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