Repeated vital sign measurements in the emergency department predict patient deterioration within 72 hours: a prospective observational study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Vincent M QuintenJan C Ter Maaten

Abstract

More than one in five patients presenting to the emergency department (ED) with (suspected) infection or sepsis deteriorate within 72 h from admission. Surprisingly little is known about vital signs in relation to deterioration, especially in the ED. The aim of our study was to determine whether repeated vital sign measurements in the ED can differentiate between patients who will deteriorate within 72 h and patients who will not deteriorate. We performed a prospective observational study in patients presenting with (suspected) infection or sepsis to the ED of our tertiary care teaching hospital. Vital signs (heart rate, mean arterial pressure (MAP), respiratory rate and body temperature) were measured in 30-min intervals during the first 3 h in the ED. Primary outcome was patient deterioration within 72 h from admission, defined as the development of acute kidney injury, liver failure, respiratory failure, intensive care unit admission or in-hospital mortality. We performed a logistic regression analysis using a base model including age, gender and comorbidities. Thereafter, we performed separate logistic regression analyses for each vital sign using the value at admission, the change over time and its variability. For each an...Continue Reading

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Citations

Apr 14, 2020·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Mathieu OberlinXavier Bobbia
Sep 30, 2020·Diagnostics·Tae Sik HwangYoung Sook Park
Jan 30, 2021·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Steve B ChukwulebeAnthony J Dean

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SepsiVit
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