Abstract
The repellent activity of Piper aduncum essential oil against Aedes albopictus was investigated under laboratory conditions with human volunteers. The lowest median effective dose (ED50) value was 1.5 microg/cm2 at 60 sec of exposure when compared to 90 sec (2.1 microg/cm2) and 120 sec (1.8 microg/cm2) of exposure. At 0.4 g, the essential oil gave a high protection (95.2%) against Ae. albopictus bites or landing at 2 h postapplication. The percentage of protection was reduced to 83.3% after 4 h, 64.5% after 6 h, and 51.6% after 8 h postapplication. As a comparison, treatment with 10% deet gave 100% protection against mosquito biting/landing for 4 h postapplication. There was no significant difference in percentage protection reduction between the plant extract and the commercial product deet, respectively (P = 0.739). The essential oil, which was not as good as deet, still gave moderate protection against Ae. albopictus biting even until 4 h postapplication. In conclusion, the P. aduncum essential oil has the potential to be used as a repellent against the dengue/dengue hemorrhagic fever vector, Ae. albopictus.
References
Jan 1, 1986·Journal of Toxicology and Environmental Health·P J Robbins, M G Cherniack
Mar 24, 1982·Journal of Medical Entomology·M D BuescherM A Moussa
May 1, 1994·Journal of Medical Entomology·V P Sharma, M A Ansari
Mar 26, 1998·Medical and Veterinary Entomology·D R BarnardC E Schreck
Jun 20, 1998·Annals of Internal Medicine·M S Fradin
Sep 16, 1998·Medical and Veterinary Entomology·R P PenillaM H Rodríguez
Nov 24, 1998·Medical and Veterinary Entomology·F ChandreP Guillet
Feb 24, 2001·Bioresource Technology·M R Venkatachalam, A Jebanesan
Jul 5, 2002·The New England Journal of Medicine·Mark S Fradin, John F Day
Dec 18, 2003·Journal of Toxicology. Clinical Toxicology·Daniel L Sudakin, Wade R Trevathan
Jun 29, 2004·Journal of Medical Entomology·J A Klun, M Debboun
Aug 18, 2004·Journal of Medical Entomology·Donald R Barnard, Rui-De Xue
Sep 7, 2004·Medical and Veterinary Entomology·N G Gratz
Apr 28, 2006·Parasitology Research·Abdelkrim Amer, Heinz Mehlhorn
Aug 10, 2006·Parasitology Research·K KamsukB Pitasawat
Oct 28, 2006·Journal of the American Mosquito Control Association·Junwei ZhuAijun Zhang
Sep 1, 1994·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·O ChokechaijaroenpornS Kongchuensin
Citations
Nov 10, 2013·Travel Medicine and Infectious Disease·Eleonora LupiPatricia Schlagenhauf
Mar 18, 2011·Malaria Journal·Marta Ferreira Maia, Sarah J Moore
Mar 19, 2014·Fitoterapia·Junaid U RehmanIkhlas A Khan
May 14, 2014·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Wasana BoonyuanTheeraphap Chareonviriyaphap
May 23, 2018·Scientific Reports·Yan FengAijun Zhang
Nov 28, 2015·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Sunaiyana SathantriphopTheeraphap Chareonviriyaphap
Sep 21, 2017·Medicines·Lianet MonzoteWilliam N Setzer
Mar 26, 2021·Malaria Journal·António B MapossaTaneshka Kruger
May 5, 2021·Parasite : Journal De La Société Française De Parasitologie·Andrea DurofilTrinidad Ruiz-Téllez