Repetitive finger movement performance differs among Parkinson's disease, Progressive Supranuclear Palsy, and spinocerebellar ataxia

Journal of Clinical Movement Disorders
Elizabeth L StegemöllerChris J Hass

Abstract

Differentiating movement disorders is critical for appropriate treatment, prognosis, and for clinical trials. In clinical trials this is especially important as effects can be diluted by inclusion of inappropriately diagnosed participants. In early disease duration phases, disorders often have overlapping clinical features, such as impairments in repetitive finger movement, making diagnosis challenging. The purpose of this pilot study was to examine and compare repetitive finger movement performance in participants diagnosed with idiopathic Parkinson's disease, Progressive Supranuclear Palsy, and spinocerebellar ataxias. Participants completed an unconstrained index finger flexion/extension movement (i.e. finger tap) in time with an incremental acoustic tone. Measures of movement rate, movement amplitude, and coefficient of variation were compared among groups. Significant differences between groups were revealed for movement rate at faster tone rates. Participants with Parkinson's disease tended to tap faster than the tone rate while participants with Progressive Supranuclear Palsy and spinocerebellar ataxia tended to tap slower. No significant differences were revealed for movement amplitude, but participants with spinocerebe...Continue Reading

References

Oct 1, 1989·Trends in Neurosciences·R L AlbinJ B Penney
Feb 1, 1982·The Tohoku Journal of Experimental Medicine·K KosakaR Nakamura
Dec 6, 2002·Journal of Neurophysiology·Keiichiro TomaMark Hallett
Jun 16, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Sarah FurtadoA Jon Stoessl
May 5, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Elizabeth L StegemöllerColum MacKinnon
Mar 4, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Judith van GaalenBart P van de Warrenburg
Oct 15, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Roman SchnieppKlaus Jahn
Jul 10, 2012·Brain Research·H AkhlaghiG F Egan
Aug 15, 2013·Neuroscience Letters·Elizabeth L StegemöllerColum D Mackinnon

❮ Previous
Next ❯

Citations

Dec 17, 2016·Expert Review of Neurotherapeutics·Stefano Caproni, Carlo Colosimo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

Related Papers

Movement Disorders : Official Journal of the Movement Disorder Society
José Luiz PedrosoOrlando G P Barsottini
Parkinsonism & Related Disorders
José Luiz PedrosoOrlando G P Barsottini
© 2022 Meta ULC. All rights reserved