Repetitive transcranial magnetic stimulation for rehabilitation of poststroke dysphagia: A randomized, double-blind clinical trial

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Juan DuXinfeng Liu

Abstract

This randomized, sham-controlled, double-blind study was conducted to investigate the effects of high-frequency versus low-frequency repetitive transcranial magnetic stimulation (rTMS) on patients with poststroke dysphagia during early rehabilitation. Forty patients with poststroke dysphagia were randomized to receive five daily sessions of sham, 3-Hz ipsilesional, or 1-Hz contralesional rTMS. Swallowing function, the severity of stroke and functional disability, and cortical excitability were examined before, immediately after five daily sessions, as well as the first, second, and third month after the last session. At baseline, no significant differences between groups were observed in terms of demographic and clinical rating scales. However, a significantly greater improvement in swallowing function as well as functional disability was observed after real rTMS when compared with sham rTMS, which remained 3 months after the end of the treatment sessions. In addition, 1-Hz rTMS increased cortical excitability of the affected hemisphere and decreased that of the non-affected hemisphere; however, 3-Hz rTMS only increased cortical excitability of the affected hemisphere. rTMS (both high and low frequency) improved swallowing reco...Continue Reading

References

Dec 1, 1992·Archives of Neurology·K L DePippoM J Reding
Jul 1, 1989·Stroke; a Journal of Cerebral Circulation·T BrottV Hertzberg
Dec 1, 1996·Journal of the Neurological Sciences·B BoroojerdiA Ferbert
Dec 31, 1997·Stroke; a Journal of Cerebral Circulation·S C CramerB R Rosen
Sep 15, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·A Pascual-LeoneM D Catalá
Nov 26, 1998·Dysphagia·J A LogemannL Colangelo
Dec 28, 1999·Brain : a Journal of Neurology·C ErtekinB Uludag
Jun 3, 2000·Stroke; a Journal of Cerebral Circulation·C ErtekinN Kiylioglu
Apr 7, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·David GowShaheen Hamdy
May 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·R DziewasP Lüdemann
Jun 19, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Alexander PeinemannHartwig Roman Siebner
Nov 5, 2005·Stroke; a Journal of Cerebral Circulation·Rosemary MartinoRobert Teasell
Oct 19, 2006·Neurophysiologie clinique = Clinical neurophysiology·J-P Lefaucheur
Jun 15, 2007·Nature Reviews. Neuroscience·Michael C Ridding, John C Rothwell
Dec 7, 2007·Dysphagia·Debra M Suiter, Steven B Leder
Sep 6, 2008·Acta Neurologica Scandinavica·E M KhedrJ C Rothwell
Sep 29, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·E M KhedrM Qaid
Oct 16, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·Eman M Khedr, Noha Abo-Elfetoh
Apr 23, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Thomas Nyffeler, René Müri
Apr 17, 2012·Annals of Rehabilitation Medicine·Leesuk KimSook Joung Lee
Jan 3, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J-W ParkK H Ryu
Jan 9, 2014·Frontiers in Human Neuroscience·Priyanka P ShahRoy H Hamilton

❮ Previous
Next ❯

Citations

May 18, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Juan DuXinfeng Liu
Nov 9, 2017·Current Atherosclerosis Reports·Elisheva R ColemanWuwei Feng
Oct 31, 2018·The Cochrane Database of Systematic Reviews·Philip M BathLisa F Everton
Nov 16, 2016·Current Opinion in Neurology·Julie BernhardtPeter Langhorne
May 26, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Christopher CabibOmar Ortega
May 4, 2017·Acta Neurologica Scandinavica·L SebastianelliR Nardone
Jun 10, 2020·Intensive Care Medicine·Sallyanne DuncanBronagh Blackwood
Dec 11, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Ivy ChengShaheen Hamdy
Jan 7, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jean-Pascal LefaucheurUlf Ziemann
Jun 4, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Mengqing ZhangShaheen Hamdy
Oct 17, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ivy Cheng, Shaheen Hamdy
Nov 8, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Ana DionísioMiguel Castelo-Branco

❮ Previous
Next ❯

Related Concepts

Related Feeds

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.