Repetitive transcranial magnetic stimulation treats postpartum depression

Brain Stimulation
Keith S GarciaMarty Caudle

Abstract

Postpartum depression (PPD) is a prevalent illness, affecting 10-15% of new mothers. PPD is the most common complication of childbirth and is a significant public health concern. It is known to adversely impact maternal-infant bonding, childrearing practices, and can lead to suicide and infanticide. The current treatment approaches to PPD are suboptimal. Many mothers are reluctant to take medication because of concerns about side effects or exposure of their newborn infant through breastfeeding. The specific aims of this study were to (1) examine acute treatment effectiveness, (2) examine response durability, and (3) assess an effect of repetitive transcranial magnetic stimulation (rTMS) on maternal bonding. Nine antidepressant-free women with PPD were given 20 rTMS treatments over 4 weeks (10Hz, 120% motor threshold, left dorsolateral prefrontal cortex). Multiple characteristics were assessed at baseline and throughout treatment. Duration of effect was assessed at 30 days, 3 months and 6 months posttreatment. Friedman's tests were conducted on Hamilton Rating Scale for Depression-24 item (HRSD-24), Edinburgh Postnatal Depression Scale (EPDS), Inventory of Depressive Symptomatology-Self-Report (IDS-SR) and Clinical Global Impre...Continue Reading

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Citations

Mar 5, 2013·Midwifery·Cara Bicking Kinsey, Judith E Hupcey
Nov 3, 2012·Neuropsychiatric Disease and Treatment·Martin Luiz MyczkowskiMarco Antônio Marcolin
Nov 29, 2012·F1000 Medicine Reports·Paul E Holtzheimer, Helen S Mayberg
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Oct 29, 2013·Translational Neuroscience·Thilinie Rajapakse, Adam Kirton
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Jun 4, 2019·La Presse médicale·Samuel BulteauAnne Sauvaget
Jun 15, 2019·Psychiatry Research·Ana Ganho-ÁvilaAna Osório

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