PMID: 4883016Nov 1, 1968Paper

Replication of coliphage M-13. I. Effects on host cells after synchronized infection

Journal of Virology
L R Brown, C E Dowell

Abstract

Techniques have been described for synchronization of bacteriophage M-13 infection of host cells. The latent period in infected cells was 10 min, and no appreciable number of intracellular phage was observed. Phage production proceeded in three phases after release of the starvation block: an initial rapid exponential rate of progeny phage release without cell lysis, a period of rate transition accompanying the resumption of host cell division, and a second, slower exponential rate of phage production which paralleled the rate of host cell division. The size of infected cells was not affected by infection, but the generation time was increased by 25%. Starved infected cells exhibited a much longer lag in attaining an exponential rate of growth upon the addition of nutrients than did an uninfected control culture.

References

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Citations

Mar 13, 2008·Nucleic Acids Research·Iwona Mruk, Robert M Blumenthal
Dec 1, 1975·CRC Critical Reviews in Microbiology·D T Denhardt
Oct 13, 1969·Molecular & General Genetics : MGG·S R Palchoudhury, V N Iyer
Aug 3, 2019·Expert Review of Vaccines·Zachariah SternLeondios G Kostrikis
Jul 27, 2017·Frontiers in Microbiology·Donald PanKarrie A Weber
Jul 1, 1972·Journal of Bacteriology·S E Russell, V N Iyer
Jun 1, 1969·Bacteriological Reviews·D A Marvin, B Hohn
Jun 7, 1976·Biochemical and Biophysical Research Communications·W G Haldenwang, J R Walker

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