PMID: 9642188Jun 27, 1998Paper

Replication terminator protein-based replication fork-arrest systems in various Bacillus species

Journal of Bacteriology
A A GriffithsR G Wake

Abstract

The replication terminator protein (RTP) of Bacillus subtilis interacts with its cognate DNA terminators to cause replication fork arrest, thereby ensuring that the forks approaching one another at the conclusion of a round of replication meet within a restricted terminus region. A similar situation exists in Escherichia coli, but it appears that the fork-arrest systems in these two organisms have evolved independently of one another. In the present work, RTP homologs in four species closely related to B. subtilis (B. atrophaeus, B. amyloliquefaciens, B. mojavensis, and B. vallismortis) have been identified and characterized. An RTP homolog could not be identified in another closely related species, B. licheniformis. The nucleotide and amino acid changes from B. subtilis among the four homologs are consistent with the recently established phylogenetic tree for these species. The GC contents of the rtp genes raise the possibility that these organisms arose within this branch of the tree by horizontal transfer into a common ancestor after their divergence from B. licheniformis. Only 5 amino acid residue positions were changed among the four homologs, despite an up to 17.2% change in the nucleotide sequence, a finding that highlig...Continue Reading

References

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May 1, 1997·Journal of Bacteriology·A A Griffiths, R G Wake
Sep 5, 1997·Science·F R BlattnerY Shao

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Citations

Jul 30, 2014·Proceedings of the National Academy of Sciences of the United States of America·Xindan WangDavid Z Rudner
Feb 15, 2000·Journal of Bacteriology·A A Griffiths, R G Wake
Mar 21, 2009·Molecular Microbiology·Daniel L Kaplan, Deepak Bastia
Oct 9, 2012·Proteins·Mohammed AlQuraishi, Harley H McAdams
Oct 6, 1999·Current Opinion in Microbiology·I MoszerA Danchin
Oct 16, 2003·Biochemical and Biophysical Research Communications·J P VivianJ A Wilce

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