Repolarization Vector Magnitude Differentiates Kawasaki Disease from Normal Children

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Daniel CortezPei-Ni Jone

Abstract

Kawasaki disease (KD) is the leading cause of acquired heart disease in children. The 12-lead electrocardiogram (ECG) changes in patients during the acute phase of KD include flattened T waves and prolonged corrected QT intervals (QTc). We set out to determine the 12-lead ECG and vectorcardiography predictors for identification of patients with KD and which of these predictors would be clinically useful for early identification of those with coronary artery anomalies (CAA). A blinded, retrospective case-control study of patients with KD and age-matched controls was performed. Deep Q waves, QTc, spatial QRS-T angles, and T-wave vector magnitude (root mean square of the T wave, RMS-T) were assessed. Comparisons between groups were performed to test for significant differences. Fifty patients with KD (mean age 3.1 ± 3.1 years, 26% female) were compared to 50 previously healthy control patients (mean age 3.8 ± 2.9 years, 44% female). Of the KD patients, 32 (64%) were diagnosed as incomplete KD and 28 (56%) of them had CAA. When compared to the control group, KD patients had abnormal Q waves (72% vs 44% P = 0.005), shorter QTc values (395.1 ± 24.7 ms vs 410.4 ± 34.7 ms, P = 0.013), and lower RMS-T (0.42 ± 0.02 mV vs 0.63 ± 0.03 mV P...Continue Reading

References

Oct 1, 1988·American Heart Journal·T NakanishiY Matsumoto
May 1, 1993·Circulation·A S DajaniW Wilson
Feb 24, 2001·Circulation·UNKNOWN Council on Cardiovascular Disease in the YoungUNKNOWN American Heart Association
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Takuya YamazakiPaul Wang
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Oct 9, 2008·The Canadian Journal of Cardiology·Matthew A CrystalBrian W McCrindle
Feb 5, 2015·The Journal of Pediatrics·Derek Q PhanRuey-Kang R Chang

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Citations

Sep 30, 2016·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Daniel CortezPei-Ni Jone
May 19, 2021·The Journal of Pediatrics·Ana Barrios-TascónUNKNOWN KAWA-RACE study group

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