Reported Primary and Secondary Syphilis Cases in the United States: Implications for HIV Infection

Sexually Transmitted Diseases
Sarah KiddHillard Weinstock

Abstract

Recent increases in syphilis among men who have sex with men (MSM) are especially concerning, given the biologic and epidemiologic associations between syphilis and HIV infection. We sought to better describe the current epidemiology of primary and secondary (P&S) syphilis and the prevalence of HIV infection among reported P&S syphilis cases by demographic group, including sex of sex partner, in the United States in 2016. We reviewed national P&S syphilis case report data from 2016, including available risk factor information such as sex of sex partner and HIV status. Data were extracted from the National Electronic Telecommunications System for Surveillance, the system through which Centers for Disease Control and Prevention receives notifiable sexually transmitted disease data from all 50 states and the District of Columbia. The proportion of cases with HIV coinfection was calculated using cases with known HIV status as the denominator. Of 27,814 P&S syphilis cases reported in 2016, 58.1% were among MSM, 13.9% were among men who have sex with women only, 11.0% were among women, and 16.9% were among men without data on sex of sex partners. Similar patterns were observed across geographic regions, race/ethnicity groups, and mos...Continue Reading

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Sep 5, 2018·Journal of Lower Genital Tract Disease·Kimberly A KilfoyleJennifer S Smith
Nov 7, 2018·Obstetrics and Gynecology·Andrea C Des MaraisJennifer S Smith
Jun 6, 2018·BMJ Case Reports·Jean-Charles CrépinLionel Piroth
Jun 11, 2020·Sexually Transmitted Diseases·Dawne DiOrioShane Hanley
Aug 28, 2020·Open Forum Infectious Diseases·Cheríe S BlairRaphael J Landovitz
Feb 26, 2021·Frontiers in Cellular and Infection Microbiology·Yuting LuoYongjian Xiao
May 13, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ann M DennisArlene C Seña

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