Representation learning for mammography mass lesion classification with convolutional neural networks

Computer Methods and Programs in Biomedicine
John ArevaloMiguel A Guevara López

Abstract

The automatic classification of breast imaging lesions is currently an unsolved problem. This paper describes an innovative representation learning framework for breast cancer diagnosis in mammography that integrates deep learning techniques to automatically learn discriminative features avoiding the design of specific hand-crafted image-based feature detectors. A new biopsy proven benchmarking dataset was built from 344 breast cancer patients' cases containing a total of 736 film mammography (mediolateral oblique and craniocaudal) views, representative of manually segmented lesions associated with masses: 426 benign lesions and 310 malignant lesions. The developed method comprises two main stages: (i) preprocessing to enhance image details and (ii) supervised training for learning both the features and the breast imaging lesions classifier. In contrast to previous works, we adopt a hybrid approach where convolutional neural networks are used to learn the representation in a supervised way instead of designing particular descriptors to explain the content of mammography images. Experimental results using the developed benchmarking breast cancer dataset demonstrated that our method exhibits significant improved performance when ...Continue Reading

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