Representation of binary pheromone blends by glomerulus-specific olfactory projection neurons

Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
T HeinbockelJohn G Hildebrand

Abstract

An outstanding challenge in olfactory neurobiology is to explain how glomerular networks encode information about stimulus mixtures, which are typical of natural olfactory stimuli. In the moth Manduca sexta, a species-specific blend of two sex-pheromone components is required for reproductive signaling. Each component stimulates a different population of olfactory receptor cells that in turn target two identified glomeruli in the macroglomerular complex of the male's antennal lobe. Using intracellular recording and staining, we examined how responses of projection neurons innervating these glomeruli are modulated by changes in the level and ratio of the two essential components in stimulus blends. Compared to projection neurons specific for one component, projection neurons that integrated information about the blend (received excitatory input from one component and inhibitory input from the other) showed enhanced ability to track a train of stimulus pulses. The precision of stimulus-pulse tracking was furthermore optimized at a synthetic blend ratio that mimics the physiological response to an extract of the female's pheromone gland. Optimal responsiveness of a projection neuron to repetitive stimulus pulses therefore appears ...Continue Reading

References

Jan 1, 1977·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·D J PrescottS Jewett
Jul 15, 1976·Developmental Biology·J R Sanes, J G Hildebrand
Jan 1, 1989·Annual Review of Entomology·U HombergJ G Hildebrand
May 1, 1987·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·T A Christensen, J G Hildebrand
Jan 1, 1996·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·J G Hildebrand
Apr 1, 1996·Chemical Senses·K E Kaissling
May 1, 1996·Journal of Neurobiology·T A ChristensenJ G Hildebrand
Jul 23, 1996·Proceedings of the National Academy of Sciences of the United States of America·W WuB S Hansson
Mar 22, 2001·Nature·N J VickersJ G Hildebrand
Apr 3, 2001·Annual Review of Neuroscience·G LaurentH D Abarbanel
Jun 8, 2001·Neuron·M de BruyneJ R Carlson
Aug 15, 2001·Current Opinion in Neurobiology·R W Friedrich, M Stopfer
Jul 26, 2002·Current Opinion in Neurobiology·Thomas A Christensen, John G Hildebrand
Feb 21, 2003·Current Opinion in Neurobiology·Andreas Keller, Leslie B Vosshall
Apr 2, 2003·Brain Research. Brain Research Reviews·Michael Leon, Brett A Johnson
Sep 10, 2003·Proceedings of the National Academy of Sciences of the United States of America·Thomas A ChristensenJohn G Hildebrand
Sep 16, 2003·Neuron·Mark StopferGilles Laurent
Nov 19, 2003·The European Journal of Neuroscience·Silke Sachse, C Giovanni Galizia
Mar 19, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Carolina E ReisenmanJohn G Hildebrand

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Citations

Jul 31, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Thomas HeinbockelCarolina E Reisenman
Sep 5, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Joshua P MartinJohn G Hildebrand
Jun 27, 2008·Journal of Chemical Ecology·Hong Lei, Neil Vickers
Apr 18, 2008·Journal of Neurophysiology·Carolina E ReisenmanJohn G Hildebrand
Aug 21, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Patricia C FernandezBrian H Smith
Oct 4, 2011·Progress in Neurobiology·Joshua P MartinJohn G Hildebrand
Mar 26, 2016·Frontiers in Physiology·Hong LeiAaditya V Rangan
Sep 1, 2015·Frontiers in Physiology·Carolina E Reisenman, Jeffrey A Riffell
May 6, 2015·Journal of Insect Physiology·Kye Chung ParkUNKNOWN Better Border Biosecurity Collaboration (B3)
Jul 15, 2015·Bioinspiration & Biomimetics·S B OlssonT C Pearce
Nov 22, 2005·Journal of Psychosomatic Obstetrics and Gynaecology·Gerard A Schuiling
Jul 23, 2016·Frontiers in Physiology·Carolina E ReisenmanPablo G Guerenstein

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