Representational overlap of adjacent fingers in multiple areas of human primary somatosensory cortex depends on electrical stimulus intensity: an fMRI study

Brain Research
Thomas KrauseArno Villringer

Abstract

Functional magnetic resonance imaging (fMRI) was used to examine the influence of non-painful electrical stimulus intensity on the BOLD response in human primary somatosensory cortex (SI). In ten healthy subjects, index and middle finger of the right hand were stimulated separately at two different stimulus intensities. The activated volume of single finger representations as well as the volume of representational overlap of the two activations increased following an increase in stimulus intensity. This effect was seen in two different subdivisions of SI, one in the depth of the central sulcus, presumably corresponding to Brodmann area (BA) 3b, and one on the crown of the postcentral gyrus, presumably corresponding to BA 1/2. Relative overlap (ratio of overlap volume to volume of individual finger representation) was larger in BA 1/2 than in BA 3b. Additionally, in both areas relative overlap increased significantly from low to high stimulus intensity. Relative overlap did not change when different correlation thresholds were employed arguing against an unspecific 'spillover effect'. Analysis of signal intensity time courses indicated that the response difference to high versus low stimulus strength was not present during the i...Continue Reading

References

Sep 1, 1979·Electroencephalography and Clinical Neurophysiology·R P LesserH Lueders
Sep 1, 1992·Journal of Magnetic Resonance Imaging : JMRI·J FrahmW Hänicke
Apr 1, 1992·Clinical EEG (electroencephalography)·M RappaportJ Leonard
Jun 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·K K KwongR Turner
Jun 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P A BandettiniJ S Hyde
Jul 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·S OgawaK Ugurbil
Jul 1, 1987·Journal of Neurosurgery·P T FoxM E Raichle
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K SakaiY Miyashita
Oct 1, 1994·Neurosurgery·T A HammekeJ R Binder
Feb 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J FrahmA Kleinschmidt
Jul 1, 1996·Journal of Magnetic Resonance Imaging : JMRI·W LinH Burton
Jan 1, 1997·Brain : a Journal of Neurology·T A YousryP Winkler
Aug 8, 1997·Psychiatry Research·S ArndtM Flaum
Jun 1, 1996·NeuroImage·A F CannestraA W Toga
Jan 8, 1998·The European Journal of Neuroscience·A KleinschmidtJ Frahm
Jun 11, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P FranssonJ Frahm
Jul 29, 1998·Electroencephalography and Clinical Neurophysiology·C GrimmC H Lücking
Jul 1, 1999·NeuroImage·J A MaldjianD C Alsop
Jul 1, 1999·NeuroImage·S GeyerK Zilles
Apr 21, 2001·Cerebral Cortex·J RubenA Villringer

❮ Previous
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Citations

Oct 13, 2001·NMR in Biomedicine
Jul 22, 2005·Experimental Brain Research·R C G HelmichA Münchau
Aug 4, 2005·Experimental Brain Research·Stefano TamburinGiampietro Zanette
Jul 12, 2002·Biological cybernetics·Vladimir M ZatsiorskyMark L Latash
Mar 17, 2004·Brain Research. Cognitive Brain Research·Aimee J NelsonWilliam E McIlroy
Feb 15, 2005·Magnetic Resonance Imaging·Carlo Adolfo PorroPatrizia Baraldi
Oct 12, 2001·Current Opinion in Neurobiology·R S Menon
Sep 2, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yasukazu Hamada, Ryoji Suzuki
Feb 5, 2008·Cerebral Cortex·Aimee J Nelson, Robert Chen
Apr 4, 2002·Neuroreport·Michael DeuchertArno Villringer
Apr 6, 2011·PloS One·Jay P WarrenStephen I Helms Tillery
Jan 4, 2013·Brain Structure & Function·Esther KuehnSimone Schütz-Bosbach
Oct 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Afonso C Silva, Alan P Koretsky
May 7, 2013·Human Movement Science·Kia Sanei, Peter J Keir
Jun 6, 2009·Magnetic Resonance Imaging·Till NierhausArno Villringer
Oct 5, 2010·NeuroImage·Elizabeth Ann StringerJohn C Gore
Nov 13, 2007·NeuroImage·Christian DreselBernhard Haslinger
Jan 9, 2013·NeuroImage·Sonja GröschelAndreas Kastrup
Jan 13, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R BikmullinaA Münchau
May 22, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Daisuke SatoAtsuo Maruyama
Jul 7, 2007·Magnetic Resonance Imaging·Na ZhangMalcolm J Avison
Jan 8, 2010·Neurorehabilitation and Neural Repair·Koen CuypersRaf L J Meesen
Dec 30, 2017·The Journal of Physiology·Franck-Emmanuel RouxJean-Baptiste Durand
Jun 5, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Stephen ButterworthGuy V Sawle
Apr 12, 2019·The Quarterly Journal of Experimental Psychology : QJEP·Antonio CataldoPatrick Haggard
Aug 28, 2015·Journal of Neurophysiology·Gijs Joost BrouwerArthur C Grant
Sep 10, 2019·The Journal of Physiology·Richard G Carson, Alison R Buick
Jul 27, 2012·Journal of Neurophysiology·Alice TomassiniMaria Concetta Morrone
Jan 20, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Fengqiao SunXiaohua Zhang

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