Representations of motivational drives in mesial cortex, medial thalamus, hypothalamus and midbrain

Brain Research Bulletin
Terence V Sewards, Mark A Sewards

Abstract

We propose that neural representations of motivational drives, including sexual desire, hunger, thirst, fear, power-dominance, the motivational aspect of pain, the need for sleep, and nurturance, are represented in four areas in the brain. These are located in the medial hypothalamic/preoptic area, the periaqueductal gray matter (PAG) in the midbrain/pons, the midline and intralaminar thalamic nuclei, and in the anterior part of the mesial cortex, including the medial prefrontal and anterior cingulate areas. We attempt to determine the locations of each of these representations within the hypothalamus/preoptic area, periaqueductal gray and cortex, based on the available literature on activation of brain structures by stimuli that evoke these forms of motivation, on the effects of electrical and chemical stimulation and lesions of candidate structures, and on hodological data. We discuss the hierarchical organization of the representations for a given drive, outputs from these representations to premotor structures in the medulla, caudate-putamen, and cortex, and their contributions to involuntary, learned-sequential (operant) and voluntary behaviors.

References

Jan 1, 1979·Clinical Neurology and Neurosurgery·L V Laitinen
Feb 1, 1977·Journal of Comparative and Physiological Psychology·M NumanB R Komisaruk
Mar 1, 1978·Brain : a Journal of Neurology·E HalgrenP H Crandall
Aug 1, 1978·Acta Physiologica Scandinavica·M Rundgren, F Fyhrquist
Feb 1, 1975·Journal of Comparative and Physiological Psychology·B Kolb, A J Nonneman
May 1, 1975·The American Journal of Physiology·M van GemertA M Moses
Nov 1, 1992·Behavioral and Neural Biology·M J Cambiasso, E Chiaraviglio
Aug 1, 1992·Behavioral Neuroscience·P Yahr, S B Greene
Jul 25, 1992·The Journal of Comparative Neurology·K IwataR L Nahin
Jul 1, 1992·Physiology & Behavior·L L BernardisL L Bellinger
Jan 1, 1991·Neuroscience·S T Meller, B J Dennis
Jun 8, 1991·The Journal of Comparative Neurology·K M HurleyC B Saper
Sep 11, 1991·The Journal of Comparative Neurology·C W Ragsdale, A M Graybiel
Mar 15, 1991·Science·J D TalbotG H Duncan
Sep 8, 1990·The Journal of Comparative Neurology·H W Berendse, H J Groenewegen
Mar 1, 1990·Brain Research Bulletin·N KinjoE Garcia-Rill
Jun 1, 1990·Journal of the Indian Medical Association·G D Shukla
Dec 1, 1990·Brain : a Journal of Neurology·P Gloor

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Citations

Dec 18, 2010·Bulletin of Experimental Biology and Medicine·A F Meshcheryakov, K V Sudakov
Sep 8, 2005·Brain Research Bulletin·András Csillag, Catherine M Montagnese
Jun 15, 2011·Cerebral Cortex·Swann PichonJulie Grèzes
Mar 27, 2012·Social Cognitive and Affective Neuroscience·Jason T BuhleTor D Wager
Feb 17, 2010·Cerebrospinal Fluid Research·Jan G Veening, Henk P Barendregt
Aug 14, 2012·Fluids and Barriers of the CNS·Jan G VeeningHenk P Barendregt
Feb 8, 2006·Proceedings of the National Academy of Sciences of the United States of America·Michael J FarrellDerek A Denton
Dec 6, 2003·Proceedings of the National Academy of Sciences of the United States of America·Gary EganDerek Denton
May 21, 2009·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Yana Suchy
Mar 17, 2007·The International Journal of Neuroscience·Marcello Spinella
Jan 31, 2016·Medical Hypotheses·A J M Loonen, S A Ivanova
Nov 20, 2015·International Journal of Impotence Research·T-H KimG-W Jeong
May 25, 2010·Physiology & Behavior·Jan G VeeningHenk P Barendregt
Dec 17, 2009·Hormones and Behavior·Karla S FrohmaderLique M Coolen
Jun 19, 2007·Neuroscience and Biobehavioral Reviews·R Andrew ChambersMarc N Potenza
Apr 29, 2006·Congenital Anomalies·Jun UdagawaHiroki Otani
Aug 11, 2007·Congenital Anomalies·Jun UdagawaHiroki Otani
Jan 19, 2006·Synapse·Eric A StoneDavid Quartermain
Feb 24, 2006·European Journal of Pain : EJP·David BorsookJon Levine
Jul 25, 2012·The Journal of Comparative Neurology·J Matthew Kittelberger, Andrew H Bass
Oct 12, 2010·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Jennifer Barrett, Alison S Fleming
Nov 10, 2009·Developmental Neurobiology·Katrina G SalvanteKeith W Sockman
Feb 5, 2008·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Tuan Zea TanChai Quek
Nov 14, 2006·Biochemical Pharmacology·Eric A StoneMichael L Lehmann

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