Representative drug susceptibility patterns for guiding design of re-treatment regimens for multidrug-resistant tuberculosis in Iran

Respirology : Official Journal of the Asian Pacific Society of Respirology
Payam TabarsiMohammad Reza Masjedi

Abstract

The prevalence of multidrug-resistant tuberculosis (MDR-TB) has increased substantially in the past 20 years, however, there are no data specific to Iran. This study investigated patients suspected to have MDR-TB, attending the TB referral hospital in Iran. All patients suspected of having MDR-TB on hospital admission in the period 2003-2005 were included in this study. Sputum from all patients was tested for smear and culture, and drug sensitivity testing was performed using the proportion method. Patients were categorized into three groups based on their history of medical treatment. Group I consisted of patients with CAT I regimen failure; Group II consisted of patients with a history of CAT II regimen failure and Group III comprised patients with a history of more than two courses of irregular CAT I anti-TB regimen. There were 105 patients recruited; 32 in Group I, 53 in Group II and 20 in Group III. There were no significant differences between the three groups in their resistance to first-line anti-TB drugs. Fifty-five patients were diagnosed with MDR-TB. The prevalence of MDR-TB was 56% (18 cases) in group I, 49% (26 cases) in group II and 55% (11 cases) in group III. No significant difference in the pattern of drug resi...Continue Reading

References

Apr 1, 1994·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·L Rigouts, F Portaels
Sep 9, 1993·The New England Journal of Medicine·M D Iseman
Apr 4, 2002·The Journal of Infectious Diseases·Christopher DyeBrian G Williams
Nov 30, 2002·BMJ : British Medical Journal·Edward D Chan, Michael D Iseman
Jan 31, 2003·Respiratory Medicine·D C S HutchisonH J Milburn
May 22, 2003·Tuberculosis·Marcos A Espinal
Sep 27, 2005·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Seyed Mehdi MirsaeidiAli Akbar Velayati
Jul 25, 2006·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Mehdi Seyed MirsaeidiGolnaz Ebrahimi

❮ Previous
Next ❯

Citations

Feb 5, 2009·Respirology : Official Journal of the Asian Pacific Society of Respirology·Richard Ruffin, Philip G Bardin
Jul 21, 2016·Journal of Global Antimicrobial Resistance·Parvaneh BaghaeiAli Akbar Velayati
Mar 22, 2013·PloS One·Carole D MitnickMercedes C Becerra

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Related Papers

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
N PadayatchiJ Quantrill
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
C HabeenzuJ N Maslow
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
M T GlerT E Tupasi
© 2021 Meta ULC. All rights reserved