Representative input load of antibiotics to WWTPs: Predictive accuracy and determination of a required sampling quantity

Water Research
Conrad MarxVolker Kuehn

Abstract

Predicting the input loads of antibiotics to wastewater treatment plants (WWTP) using certain input data (e.g. prescriptions) is a reasonable method if no analytical data is available. Besides the spatiotemporal uncertainties of the projection itself, only a few studies exist to confirm the suitability of required excretion data from literature. Prescription data with a comparatively high resolution and a sampling campaign covering 15 months were used to answer the question of applicability of the prediction approach. As a result, macrolides, sulfamethoxazole and trimethoprim were almost fully recovered close to 100% of the expected input loads. Nearly all substances of the beta-lactam family exhibit high elimination rates during the wastewater transport in the sewer system with a low recovery rate at the WWTP. The measured input loads of cefuroxime, ciprofloxacin and levofloxacin fluctuated greatly through the year which was not obvious from relatively constant prescribed amounts. The latter substances are an example that available data are not per se sufficient to monitor the actual release into the environment. Furthermore, the extensive data pool of this study was used to calculate the necessary number of samples to determi...Continue Reading

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Citations

Dec 9, 2015·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Patrick TimpelJoachim Fauler
Oct 4, 2016·The Science of the Total Environment·QuocTuc DinhMarc Chevreuil
Nov 20, 2016·Water Science and Technology : a Journal of the International Association on Water Pollution Research·Ekkehard ChristoffelsFranz Michael Mertens
Jun 20, 2020·Environmental Toxicology and Chemistry·Ewelina KortesmäkiLeif Kronberg
Apr 2, 2021·Environmental Science and Pollution Research International·Rong HuangLin Zhao
Jun 15, 2020·International Journal of Hygiene and Environmental Health·Tanguy PouzolJean-Luc Bertrand-Krajewski
Jun 25, 2021·Environmental Science and Pollution Research International·Carla LopezCharles W Knapp
Jul 28, 2021·Water Science and Technology : a Journal of the International Association on Water Pollution Research·T GehringM Wichern
Feb 12, 2020·The Science of the Total Environment·Thomas Thiebault

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