Reprint of: SYMPOSIUM ON CEREBROVASCULAR DISEASES. Pathogenesis, Natural History, and Treatment of Unruptured Intracranial Aneurysms

The Neuroradiology Journal
David O WiebersRobert D Jr Brown

Abstract

Unruptured intracranial aneurysms (UIAs) are a major public health issue. These lesions have become increasingly recognized in recent years with the advent of advanced cerebral imaging techniques. Epidemiological evidence from multiple sources suggests that most intracranial aneurysms do not rupture. Therefore, it is desirable to identify which UIAs are at greatest risk of rupture when considering which to repair. It is important to compare size-, site-, and group-specific natural history rates with size-, site-, and age-specific morbidity and mortality associated with UIA repair because increased natural history risk often is associated with increased risk of aneurysm repair. Patient age is crucial in decision making because of its major effect on operative morbidity and mortality; however, it does not substantially affect natural history. The effect of age is most notable in patients about 50 years of age and older for open surgery and about 70 years of age and older for endovascular procedures. In general, rupture risk is lowest for patients in asymptomatic group 1 (no history of subarachnoid hemorrhage) with UIAs less than 7 mm in diameter in the anterior circulation. Surgical morbidity and mortality are most favorable for ...Continue Reading

References

Jun 1, 1979·Journal of Neurosurgery·J Suzuki, T Onuma
Mar 1, 1979·Stroke; a Journal of Cerebral Circulation·H P AdamsC G Drake
Apr 1, 1978·Journal of Neurosurgery·N Kodama, J Suzuki
Nov 1, 1978·Journal of Neurology, Neurosurgery, and Psychiatry·J Jakubowski, B Kendall
May 1, 1977·Archives of Neurology·W F McCormick, E J Schmalstieg
Jun 1, 1977·Journal of Neurosurgery·D S SamsomW K Clark
Sep 1, 1976·Journal of Neurosurgery·L H FinneyR E Anderson
Sep 1, 1976·Radiology·M SarwarA E Zimmer
Dec 1, 1976·Journal of Neurosurgery·J M Allcock, P B Canham
Sep 24, 1992·The New England Journal of Medicine·D O Wiebers, V E Torres
Dec 1, 1990·Neurological Research·G Yong-Zhong, H A van Alphen
Feb 1, 1990·Surgical Neurology·D O Wiebers, J P Whisnant
Aug 1, 1990·Journal of Neurosurgery·B J RiceC G Drake
May 1, 1989·Stroke; a Journal of Cerebral Circulation·J P BroderickE J Bergstralh
Mar 1, 1988·Journal of Neurosurgery·R D BrownR J Maciunas
Jan 1, 1987·Journal of Neurosurgery·D O WiebersW M O'Fallon
Jan 1, 1985·Stroke; a Journal of Cerebral Circulation·A NishimotoJ Suzuki
Apr 1, 1974·Journal of Neurosurgery·K K Jain
Apr 1, 1972·Canadian Journal of Physiology and Pharmacology·S ScottM R Roach
May 1, 1970·Circulation Research·J E Foreman, K J Hutchison
Mar 1, 1970·Neurology·R M BannermanC J Graf
Oct 1, 1970·Journal of Neurosurgery·W F McCormick, G J Acosta-Rua
Nov 1, 1970·Journal of Neurosurgery·G G Ferguson
Oct 1, 1965·The British Journal of Radiology·G H Du Boulay
Aug 1, 1966·American Journal of Surgery·E J WylieA J Palubinskas
Dec 1, 1966·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·A J PalubinskasT H Newton
May 1, 1983·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C G IglesiasL T Kurland
May 1, 1983·Neurosurgery·F P WirthR M Scott
Jul 1, 1983·Surgical Neurology·M YabumotoN Komai
Jul 1, 1983·Surgical Neurology·F TognettiC Testa
Feb 1, 1981·Neurosurgery·L N Sekhar, R C Heros
Oct 1, 1980·Neurology·L H PhillipsT M Sundt
Jan 1, 1980·Archives of Neurology·D J ZacksJ D Miller
Jul 1, 1980·Journal of Neurosurgery·J L Salazar
Jan 1, 1980·Acta neurochirurgica·M ScanariniD L Fiore
Mar 19, 1981·The New England Journal of Medicine·D O WiebersW M O'Fallon

❮ Previous
Next ❯

Citations

Aug 12, 2015·Nature Reviews. Nephrology·Ronald D PerroneTerry Watnick

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.