PMID: 11606349Oct 19, 2001Paper

Reproducibility and interchangeability of the Thromboelastograph, Sonoclot and Hemochron activated coagulation time in cardiac surgery

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
F ForestierJ F Hardy

Abstract

Despite their common use in cardiac surgery, few studies have evaluated the reproducibility of the Thromboelastograph (TEG), of the Sonoclot (SCT), and of the activated coagulation time with celite (ACT-C) or kaolin (ACT-K) measured with the Hemochron, in clinical conditions of on-site monitoring of hemostasis. This study determined the reproducibility of those measurements, and evaluated the ability of various devices to substitute for the ACT-C. Blood samples collected from 20 volunteers and 21 patients undergoing myocardial revascularization were analyzed in the two channels of the TEG, in two SCT and four Hemochron analyzers. The overall of TEG and SCT coagulation profiles were analyzed by a computerized TEG and an experienced observer respectively. The variation rate (V%) was calculated for each variable. The ability of ACT-K and SCT to substitute for ACT-C under different clinical conditions was evaluated. ACT-C and ACT-K V% ranged between 5.6% and 10.8% and between 6.7% and 12.4% respectively. TEG and SCT V% ranged between 3.1% and 9.5% and between 5.8% and 33.6% respectively, according to different conditions and parameters. In volunteers and non-heparinized patients, the ACT-C and ACT-K were interchangeable. No other t...Continue Reading

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Citations

Apr 19, 2008·Anesthesia and Analgesia·Michael T Ganter, Christoph K Hofer
Jun 13, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Pierre Sié, Annick Steib
Mar 31, 2011·Veterinary Clinical Pathology·Maureen A McMichael, Stephanie A Smith
Jun 10, 2014·Scandinavian Journal of Clinical and Laboratory Investigation·Sacha SølbeckPär I Johansson
Jun 13, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·André VincentelliSylvain Bélisle
Jun 17, 2021·Veterinary Clinical Pathology·Yekaterina BurikoDeborah C Silverstein
Dec 17, 2009·British Journal of Anaesthesia·L J Enriquez, L Shore-Lesserson

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