PMID: 9445501Jan 31, 1998Paper

Reproducibility of 24-hour intraesophageal pH monitoring in pediatric patients

Pediatrics
L MahajanM Kay

Abstract

Despite the widespread use of 24-hour intraesophageal pH monitoring for evaluation of gastroesophageal reflux in infants and children, there is little published information regarding the reproducibility of ambulatory pH studies in this patient population. The purpose of our study was to evaluate the reproducibility of 24-hour intraesophageal pH monitoring in pediatric patients. We prospectively investigated 26 patients with symptoms suggestive of gastroesophageal reflux (14 females and 12 males) ranging in age from 1 month to 18 years (mean, 9.2 years). The patients underwent extended intraesophageal pH monitoring over two consecutive 24-hour periods. Data analysis revealed that the overall reproducibility of ambulatory 24-hour pH monitoring is only 69% (r = 0.32). Eight of 26 patients had conflicting results on day 1 compared with results on day 2. Of the 8 patients with conflicting results on day 1 versus day 2, 5 had normal studies on day 1, but demonstrated pathologic reflux on day 2. Thus, the false-negative rate for day 1 was 19.2%. The kappa statistic calculated for the total time the pH was abnormal was 0.32, with values < 0.4 representing poor correlation. Spearman correlation coefficients indicated that the percentage...Continue Reading

Citations

Feb 17, 2005·Digestive Diseases and Sciences·Vasundhara ToliaRonald Thomas
Mar 12, 2002·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Krystyna Wasowska-KrólikowskaAneta Krogulska
Jan 15, 2000·Journal of Paediatrics and Child Health·W S LeeJ A Walker-Smith
Aug 30, 2001·Journal of Pediatric Gastroenterology and Nutrition·C D RudolphUNKNOWN North American Society for Pediatric Gastroenterology and Nutrition
May 17, 2000·Current Opinion in Pulmonary Medicine·B E Chipps, D R Chipps
Dec 17, 2009·Italian Journal of Pediatrics·Flavia IndrioRuggiero Francavilla
Jun 28, 2005·Paediatric Drugs·Mark D ScarupaBrendan J Canning
Apr 8, 2009·Journal of Clinical Gastroenterology·Brian E LacyKim Ornvold
Jul 23, 2005·Scandinavian Journal of Gastroenterology·Ketil StørdalLeiv Sandvik
Feb 10, 2016·International Journal of Pediatric Otorhinolaryngology·Melanie DuvalAlbert H Park
May 20, 2011·The Journal of Pediatrics·Eric Hassall
Jul 22, 2015·Journal of Pediatric Gastroenterology and Nutrition·Anupama RaviJames Berman
Aug 13, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·L RodriguezS Nurko
May 12, 2006·American Journal of Medical Genetics. Part a·Giuseppe MartuccielloRichard J Gibbons
Aug 12, 1999·Journal of Pediatric Surgery·S BouchardA Bensoussan
Dec 20, 2005·International Journal of Pediatric Otorhinolaryngology·Pelagia Stavroulaki
Nov 22, 2007·Journal of Pediatric Gastroenterology and Nutrition·Joseph M CroffieSteven K Dadzie
Jul 11, 2018·International Journal of Qualitative Studies on Health and Well-being·Joanna GoldthorpeRachel Calam
Oct 6, 2005·Journal of Pediatric Gastroenterology and Nutrition·Jay A Hochman, Jennifer Favaloro-Sabatier

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