PMID: 8942887Nov 1, 1996Paper

Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography

Ophthalmology
J S SchumanE A Swanson

Abstract

Optical coherence tomography (OCT) is a new technology that uses near-infrared light in an interferometer to produce approximately 10-microns resolution cross-sectional images of the tissue of interest. The authors performed repeated quantitative assessment of nerve fiber layer thickness in individuals with normal and glaucomatous eyes, and they evaluated the reproducibility of these measurements. The authors studied 21 eyes of 21 subjects by OCT. Each subject underwent five repetitions of a series of scans on five separate occasions within a 1-month period. Each series consisted of three circular scans around the optic nerve head (diameters, 2.9, 3.4, and 4.5 mm). Each series was performed separately using internal (fixation with same eye being studied) and external (fixation with contralateral eye) fixation techniques. The eye studied and the sequence of testing were assigned randomly. Internal fixation (IF), in general, provides a slightly higher degree of reproducibility than external fixation (EF). Reproducibility was better in a given eye on a given visit than from visit to visit. Reproducibility as measured by intraclass correlation coefficients were as follows: circle diameter (CD), 2.9 mm, 0.51/0.57 (normal/glaucoma) (...Continue Reading

References

May 1, 1995·American Journal of Ophthalmology·R N WeinrebL Zangwill
May 1, 1995·Ophthalmology·M R HeeJ G Fujimoto
Mar 1, 1995·Archives of Ophthalmology·M R HeeJ G Fujimoto
May 1, 1993·Archives of Ophthalmology·R N WeinrebD Morsman
Apr 1, 1994·Journal of Glaucoma·H D HoskinsS R Verdooner

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Citations

Apr 13, 2005·Archives of Ophthalmology·Gadi WollsteinLelia A Paunescu
Feb 28, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A G BöhmL E Pillunat
Jan 22, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rodrigo Luz MeirellesMichel Eid Farah
Aug 6, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Esther M HoffmannFranz H Grus
Jul 27, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Akiyasu KanamoriAkira Negi
Sep 24, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Argyrios TzamalisIvan Haefliger
Oct 16, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Barbara Cvenkel, Alenka Sket Kontestabile
Feb 22, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yaroslava WennerBirgit Lorenz
Sep 13, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Marc Töteberg-HarmsMarcel N Menke
Apr 17, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Berthold PempAndreas Reitner
Sep 5, 2009·Journal of Neural Transmission·Ivan Bodis-Wollner
Feb 13, 2010·Japanese Journal of Ophthalmology·Makoto KannoHidetoshi Yamashita
Nov 6, 2010·Japanese Journal of Ophthalmology·Fumiko Ikeda, Shoji Kishi
Dec 31, 2010·Japanese Journal of Ophthalmology·Suhwan LeeMichael S Kook
Feb 14, 2004·American Journal of Ophthalmology·Kouros Nouri-MahdaviJoseph Caprioli
Jun 1, 2001·American Journal of Ophthalmology·J Caprioli
Mar 5, 2003·American Journal of Ophthalmology·Felipe A MedeirosRemo Susanna
Dec 31, 2002·Survey of Ophthalmology·Claudia Auw-HaedrichHeinrich Witschel
Jul 23, 1999·Survey of Ophthalmology·D C BroadwayS M Drance
Apr 23, 2004·Ophthalmology Clinics of North America·Daniel M SteinJoel S Schuman
Aug 6, 2008·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Pai-Huei Peng, Huey-Shyan Lin
Oct 23, 2002·Acta Ophthalmologica Scandinavica. Supplement·R G Carassa
Oct 23, 2002·Acta Ophthalmologica Scandinavica. Supplement·A GiovanniniC Mariotti
Apr 3, 2001·Nature Medicine·W DrexlerJ G Fujimoto

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