Reproducibility of the Heidelberg retinal flowmeter in determining low perfusion areas in peripapillary retina

The British Journal of Ophthalmology
C Jonescu-CuypersA L Coleman

Abstract

To evaluate the interobserver variability and retest reproducibility of confocal scanning laser Doppler flowmeter in measuring capillary perfusion of the peripapillary retina. Blood flow measurements were performed in one eye of 10 normal subjects by two investigators on two different days (visits). Five separate measurements of the peripapillary blood flow parameters were recorded by each observer at each visit. The Heidelberg retina flowmeter was used to record capillary perfusion in a 2560x640 microm area of the superotemporal peripapillary region and pixel by pixel analysis was done from an area adjacent to the optic disc, with a minimum of 1600 pixels. The percentage of pixels with less than 1 arbitrary unit of flow (no flow) and 10, 25, 50, 75, 90th percentiles of flow values was calculated. Interobserver measurements were compared by paired t test. Intraclass correlations (ICC) were used to determine the interobserver variability and retest reproducibility of the measurements. Intrasession coefficients of variations (CV) were also calculated. There were no statistically significant differences between the two observers for all measurements and between visits for the percentage of pixels with no flow. ICC was 66% (range 5...Continue Reading

References

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Apr 1, 1997·Ophthalmology·G Michelson, J Harazny
Aug 1, 1997·Journal of Glaucoma·B C Chauhan, F M Smith
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Feb 24, 2004·The British Journal of Ophthalmology·C P Jonescu-CuypersG K Krieglstein

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Citations

Mar 19, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jung Hyun ParkHyeong Gon Yu
May 24, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jay ChhablaniWilliam R Freeman
Nov 2, 2006·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Brent SieskyMiriam Zalish
May 26, 2006·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Tulay SimsekOrhan Zilelioglu
Apr 15, 2009·Journal of Glaucoma·Itay Ben ZionHanna J Garzozi
Jun 24, 2008·Current Eye Research·Andreas J KreisTien Y Wong
Mar 8, 2012·Clinical & Experimental Ophthalmology·Yochai ShoshaniBrent A Siesky
Dec 23, 2014·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Rachael A O'ConnellBang V Bui
May 15, 2018·Current Eye Research·Sunee Chansangpetch, Shan C Lin
Jan 4, 2019·The British Journal of Ophthalmology·Brent SieskyAlice C Verticchio Vercellin
Oct 12, 2017·Ophthalmic Surgery, Lasers & Imaging Retina·Thalmon R CampagnoliWilliam E Smiddy
Dec 25, 2013·European Journal of Ophthalmology·Eric LeeJohn Ling

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