PMID: 9181839Mar 1, 1997Paper

Reproducibility of the pattern electroretinogram

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
T Otto, M Bach

Abstract

The pattern ERG (PERG) is used as an indicator of retinal ganglion cell function. Up to now, reports on the reproducibility of the PERG have been contradictory. We investigated the reproducibility under the conditions of the forthcoming ISCEV guidelines for the PERG. We simultaneously recorded the PERG and VEP in 42 eyes of 21 subjects to phase-reversing checkerboard stimuli with DTL electrodes. Both transient (2 rps) and steady-state (16 rps) stimulation was employed. The check sizes were 0.4 degree, 0.8 degree and 16 degrees, the mean luminance 45 cd/m2, the contrast 98%, and the field size 32 degrees x 27 degrees. Measurements were repeated at the same time of day after 1 week. In addition, we compared two different electrode positions in 16 eyes: (1) across the cornea along the lower lid; and deep in the conjunctival sac. With position (1) the amplitudes were found to be higher by 20% than (2). We calculated the coefficient of variation (CV) of amplitude as a measure of reproducibility. CV was 7 +/- 1% for the steady-state PERG, 9 +/- 1% for the transient PERG, 12 +/- 2% for the steady-state VEP and 14 +/- 3% for the transient VEP. For the latency of the PERG, the intersession CV was found to be 1.5%. Amplitude reproducibil...Continue Reading

Citations

Jul 4, 2018·Documenta Ophthalmologica. Advances in Ophthalmology·Ewelina Lachowicz, Wojciech Lubiński
Nov 7, 2019·Documenta Ophthalmologica. Advances in Ophthalmology·Anna H BrouwerMaria M van Genderen
Oct 22, 2013·Documenta Ophthalmologica. Advances in Ophthalmology·Joanna KaraśkiewiczWojciech Lubiński
Sep 26, 2016·Documenta Ophthalmologica. Advances in Ophthalmology·Ángel García-GarcíaGema Rebolleda
May 22, 2001·Clinical EEG (electroencephalography)·Z MariI Bodis-Wollner
Oct 2, 2019·Documenta Ophthalmologica. Advances in Ophthalmology·Ana Amorim-de-SousaJosé M González-Méijome
Mar 26, 2011·Documenta Ophthalmologica. Advances in Ophthalmology·Tessa B MellowDorothy A Thompson
Feb 23, 2017·Documenta Ophthalmologica. Advances in Ophthalmology·A KurtenbachH Langrová

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