Reproducibility of time-domain indexes of heart rate variability in patients with vasovagal syncope

The American Journal of Cardiology
G E KochiadakisP E Vardas

Abstract

The aim of this study was to examine whether the indexes of heart rate variability (HRV) are stable from day-to-day in patients with vasovagal syncope and whether the stability of the HRV indexes is linked with that of the clinical results of the tilt test. Nineteen patients with a history of syncopal episodes and a positive tilt test underwent a second test 1 week later. Of these, 11 (group P-P) also had a positive second test, whereas 8 (group P-N) had a negative second test. Fifteen healthy volunteers served as a control group. Five time domain indexes were derived: the mean of all coupling intervals between normal beats (mean NN), the SD about the mean of all coupling intervals between normal beats (SDNN), the mean of all 5-minute standard deviations of NNs (SD), the proportion of adjacent normal RR intervals differing by >50 ms (pNN50), the root-mean-square of the difference between successive RRs (rMSSD) and the standard deviations of 5-minute mean NN intervals (SDANN). The control group showed good reproducibility of all HRV indexes (slope 0.86 to 0.97). The syncopal patients taken as a whole had significantly less reproducibility than the controls in the pNN50 parameter. This difference was due entirely to the patients ...Continue Reading

References

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Citations

Mar 28, 2003·International Journal of Cardiology·Dursun AlehanSencan Ozme
Jun 17, 1999·Japanese Heart Journal·M SumiyoshiY Nakata
Apr 6, 1999·The American Journal of Cardiology·A LagiC Tamburini
Mar 27, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·George KochiadakisPanos Vardas
Oct 16, 1999·The Journal of Clinical Endocrinology and Metabolism·B M SchmidtM Wehling

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