Reproducibility study of whole-brain 1H spectroscopic imaging with automated quantification.

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Meng GuD M Spielman

Abstract

A reproducibility study of proton MR spectroscopic imaging ((1)H-MRSI) of the human brain was conducted to evaluate the reliability of an automated 3D in vivo spectroscopic imaging acquisition and associated quantification algorithm. A PRESS-based pulse sequence was implemented using dualband spectral-spatial RF pulses designed to fully excite the singlet resonances of choline (Cho), creatine (Cre), and N-acetyl aspartate (NAA) while simultaneously suppressing water and lipids; 1% of the water signal was left to be used as a reference signal for robust data processing, and additional lipid suppression was obtained using adiabatic inversion recovery. Spiral k-space trajectories were used for fast spectral and spatial encoding yielding high-quality spectra from 1 cc voxels throughout the brain with a 13-min acquisition time. Data were acquired with an 8-channel phased-array coil and optimal signal-to-noise ratio (SNR) for the combined signals was achieved using a weighting based on the residual water signal. Automated quantification of the spectrum of each voxel was performed using LCModel. The complete study consisted of eight healthy adult subjects to assess intersubject variations and two subjects scanned six times each to ass...Continue Reading

References

Jan 1, 1991·Magnetic Resonance Imaging·P A NarayanaD P Flamig
Jan 1, 1989·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J FrahmR Sauter
Jan 1, 1987·Annals of the New York Academy of Sciences·P A Bottomley
Feb 1, 1985·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A Macovski
Apr 1, 1985·Physics in Medicine and Biology·A HaaseD Matthaei
Jan 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S PosseD Le Bihan
Jul 1, 1994·Journal of Magnetic Resonance Imaging : JMRI·E F JacksonP A Narayana
Dec 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S W Provencher
May 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C I HauptA A Maudsley
Jan 1, 1996·Magnetic Resonance Imaging·I MarshallR J Sellar
Jun 11, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E AdalsteinssonD M Spielman
Feb 20, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W M BrooksC A Stidley
Aug 10, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G H Glover
Jun 19, 2001·NMR in Biomedicine·S W Provencher
Dec 18, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A A SchrickerD B Vigneron
Mar 1, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Belinda S Y LiOded Gonen
Sep 28, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Dong-Hyun KimDaniel M Spielman
Feb 22, 2005·Journal of Magnetic Resonance Imaging : JMRI·Nimrod Maril, Robert E Lenkinski
Jan 1, 1991·IEEE Transactions on Medical Imaging·J PaulyA Macovski

❮ Previous
Next ❯

Citations

Feb 27, 2014·Radiology·Gülin OzUNKNOWN MRS Consensus Group
Mar 20, 2010·Psychiatry Research·Neva M CorriganStephen R Dager
Jan 21, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Neil E WilsonM Albert Thomas
Oct 1, 2011·Journal of Magnetic Resonance Imaging : JMRI·Miriam W LagemaatTom W J Scheenen
Apr 21, 2012·Journal of Magnetic Resonance Imaging : JMRI·Mingming ZhuHarlan E Shannon
Nov 29, 2014·Journal of Magnetic Resonance Imaging : JMRI·Angèle LecocqJean-Philippe Ranjeva
Sep 25, 2009·NMR in Biomedicine·A A MaudsleyS Sheriff
Sep 4, 2010·Journal of Magnetic Resonance Imaging : JMRI·Susan M NoworolskiDaniel B Vigneron
May 14, 2020·NMR in Biomedicine·Wolfgang BognerAnke Henning
Mar 2, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Charles GasparovicRex E Jung
Apr 7, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Wei LinArne Reykowski
Jan 13, 2015·NMR in Biomedicine·B L van de BankT W J Scheenen
Mar 7, 2014·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Shang-Yueh TsaiYi-Ru Lin
Mar 29, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xiao-Qi DingHeinrich Lanfermann
Mar 2, 2017·Journal of Biomedical Science·Oun Al-IedaniSaadallah Ramadan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.

Related Papers

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Belinda S Y LiOded Gonen
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Deanna L LangerAndrei Z Damyanovich
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Shang-Yueh TsaiFa-Hsuan Lin
Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Fa-Hsuan LinStefan Posse
© 2022 Meta ULC. All rights reserved