Reproducible Matrix Deposition for MALDI MSI Based on Open-Source Software and Hardware

Journal of the American Society for Mass Spectrometry
Markus Stoeckli, Dieter Staab

Abstract

The new open-source software and hardware matrix deposition device named iMatrixSpray was optimized and specified for homogeneity, reproducibility, and sensitivity in MS imaging experiments. The results confirm the design claims, with the device delivering uniform coatings with a constant quality from experiment to experiment. The robustness in combination with the open design allows developing and sharing of matrix deposition and sample preparation protocols between labs. This tool therefore enables researchers to enter the field of MALDI MSI without previous experience in matrix coating.

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Citations

Jul 16, 2016·Mass Spectrometry Reviews·Matthew B O'RourkeMatthew P Padula
Aug 16, 2016·Bioanalysis·Andrea E SteuerThomas Kraemer
Sep 15, 2016·Journal of the American Society for Mass Spectrometry·Kevin BenhamThomas M Orlando
May 26, 2017·Expert Review of Proteomics·Enzo ScifoMaciej Lalowski
Sep 23, 2018·Expert Review of Proteomics·Jenny LeopoldJürgen Schiller
Jan 9, 2019·Journal of the American Society for Mass Spectrometry·Kevin BenhamThomas M Orlando
Jan 18, 2020·Rapid Communications in Mass Spectrometry : RCM·Keiko KuwataYasuhide Naito
Jun 6, 2020·Mass Spectrometry Reviews·Enrico DavoliLavinia Morosi
Apr 24, 2018·Analytical and Bioanalytical Chemistry·Cosima Damiana CalvanoFrancesco Palmisano
Nov 21, 2018·Journal of the American Society for Mass Spectrometry·Antonín BednaříkJan Preisler
Dec 6, 2018·Analytical Chemistry·Roberto FernándezJosé A Fernández

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