Reproduction recovery of the crustacean Daphnia magna after chronic exposure to ibuprofen.

Ecotoxicology
Yuya HayashiRichard M Sibly

Abstract

In mammals, the pharmaceutical ibuprofen (IB), a non-steroidal anti-inflammatory drug, primarily functions by reversibly inhibiting the cyclooxygenase (COX) pathway in the synthesis of eicosanoids (e.g. prostaglandins). Previous studies suggest that IB may act in a similar manner to interrupt production of eicosanoids reducing reproduction in the model crustacean Daphnia magna. On this basis withdrawal of IB should lead to the recovery of D. magna reproduction. Here we test whether the effect of IB is reversible in D. magna, as it is in mammals, by observing reproduction recovery following chronic exposure. D. magna (5-days old) were exposed to a range of IB concentrations (0, 20, 40 and 80 mg l(-1)) for 10 days followed by a 10 day recovery period in uncontaminated water. During the exposure period, individuals exposed to higher concentrations produced significantly fewer offspring. Thereafter, IB-stressed individuals produced offspring faster during recovery, having similar average population growth rates (PGR) (1.15-1.28) to controls by the end of the test. It appears that maternal daphnids are susceptible to IB during egg maturation. This is the first recorded recovery of reproduction in aquatic invertebrates that suffered ...Continue Reading

References

Jan 1, 1993·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·E P SpazianiS C Edwards
May 23, 2001·Archives of Biochemistry and Biophysics·T YokomizoT Shimizu
Nov 1, 2002·The Journal of Experimental Zoology·Allen W Olmstead, Gerald A Leblanc
Sep 25, 2003·Chemosphere·Norihisa TatarazakoTaisen Iguchi
Mar 18, 2004·Archives of Insect Biochemistry and Physiology·M N MedeirosE A Machado
Dec 17, 2004·The Journal of Experimental Biology·Andrew F RowleyAnthony S Clare
Dec 8, 2005·Annual Review of Entomology·David Stanley
Jul 11, 2006·BMC Genomics·Lars-Henrik HeckmannAmanda Callaghan
May 29, 2007·Ecotoxicology·Lars-Henrik HeckmannAmanda Callaghan
Jul 31, 2007·Toxicology Letters·Lars-Henrik HeckmannRichard M Sibly

❮ Previous
Next ❯

Citations

Aug 8, 2009·Archives of Environmental Contamination and Toxicology·Iwaki NishiSukeo Onodera
Aug 31, 2012·Environmental Science and Pollution Research International·Paula PaígaCristina Delerue-Matos
Aug 1, 2013·Environmental Science & Technology·Jacob K StanleyNatàlia Garcia-Reyero
Jul 16, 2008·Frontiers in Zoology·Lars-Henrik HeckmannAmanda Callaghan
Jan 9, 2016·The Science of the Total Environment·Myriam BorgattaNathalie Chèvre
Jan 27, 2016·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Vera KovacevicMyrna J Simpson
May 9, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Nina SchlotzDominik Martin-Creuzburg
Sep 8, 2015·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Lan WangShuang Bao
Sep 24, 2013·The Science of the Total Environment·Esmeralda EstevezMaria Pino Palacios-Diaz
Jul 17, 2012·The Science of the Total Environment·N ColladoI Rodriguez-Roda
Apr 29, 2014·Regulatory Toxicology and Pharmacology : RTP·Camille Bouissou-SchurtzDominique Masset
Jun 1, 2018·Water Science and Technology : a Journal of the International Association on Water Pollution Research·H AbdelrahmanK A Gilbride
Sep 12, 2015·Water Science and Technology : a Journal of the International Association on Water Pollution Research·Gianluigi ButtiglieriIgnasi Rodriguez-Roda
Jul 21, 2015·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Iwaki NishiSukeo Onodera
Nov 1, 2020·The Science of the Total Environment·Angelika TkaczykBrygida Ślaska
Jan 27, 2021·Environmental Pollution·Klaudia ŚwiackaKatarzyna Smolarz
Dec 4, 2020·Chemosphere·Aleksandra Szabelak, Adam Bownik
Mar 20, 2021·Environmental Science and Pollution Research International·Ana Paula Sousa, Bruno Nunes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.