PMID: 11313110Apr 21, 2001Paper

Reproductive and neurobehavioural toxicity study of erythrosine administered to mice in the diet

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
T Tanaka

Abstract

Erythrosine was given in the diet to provide levels of 0 (control), 0.005, 0.015 and 0.045% from 5 weeks of age of the F(0) generation to 9 weeks of age of the F(1) generation in mice, and selected reproductive and neurobehavioural parameters were measured. There were no adverse effects of erythrosine on either litter size, litter weight or sex ratio at birth. The average body weight of the offspring was significantly increased in the middle-dose group in both sexes during the lactation period. In behavioural developmental parameters, any variables showed no significant adverse effects in either sex in the lactation period. In movement activity of exploratory behaviour, several parameters were significantly changed in the high-dose group, and those effects were dose related in adult females in the F(0) and F(1) generations and in male offspring in the F(1) generation. The dose level of erythrosine in the present study produced few adverse effects in reproductive and neurobehavioural parameters in mice.

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Citations

Jan 23, 2013·Environmental Science and Pollution Research International·Puthiya Veetil NidheeshSrikrishnaperumal Thanga Ramesh
Jul 30, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Panagiotis MpountoukasTheodore Lialiaris
Aug 12, 2015·Microscopy Research and Technique·Yasuaki NagaoAkira Mizoguchi
Sep 23, 2006·Journal of Colloid and Interface Science·Vinod K GuptaJyoti Mittal
Feb 23, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Betul Mermi CeyhanEsin Kulac
Feb 11, 2012·Toxicology and Industrial Health·Duygu Kumbul DogucFatih Gultekin
Apr 24, 2008·Toxicology and Industrial Health·Selene ChouChristopher De Rosa
Jul 1, 2014·Comprehensive Reviews in Food Science and Food Safety·Márcio CarochoIsabel C F R Ferreira
Apr 11, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·G A ChappellS J Borghoff
Mar 8, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Robinan GentryHarvey Clewell
Apr 20, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Robinan GentryAleksandra Mostrag
Jun 19, 2021·Journal of Pharmacological and Toxicological Methods·Andrew A BieberichLaszlo Urban

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