Reproductive isolation between chromosomal races of the house mouse Mus musculus domesticus in a parapatric contact area revealed by an analysis of multiple unlinked loci

Journal of Evolutionary Biology
P FranchiniE Capanna

Abstract

The house mouse, Mus musculus domesticus, exhibits a high level of chromosomal polymorphism because of the occurrence and fast fixation of Robertsonian fusions between telocentric chromosomes. For this reason, it has been considered a classical speciation model to analyse the role of the chromosomal changes in reproductive isolation. In this study, we analysed a parapatric contact area between two metacentric races in central Italy, the Cittaducale race (CD: 2n = 22) and the Ancarano race (ACR: 2n = 24), to estimate gene flow at the boundary. Hybrids between these two races show high levels of structural heterozygosity and are expected to be highly infertile. A sample of 88 mice from 14 sites was used. The mice were genotyped by means of eight microsatellite loci mapped in four different autosomal arms. The results show clear genetic differentiation between the CD and ACR races, as revealed by differences in allele frequencies, factorial correspondence analysis and indexes of genetic population (e.g. F(ST) and R(ST)) along the contact zone. The genetic differentiation between the races was further highlighted by assignation and clustering analyses, in which all the individuals were correctly assigned by their genotypes to the s...Continue Reading

References

Dec 1, 1982·Archives of Andrology·W MalorniC De Martino
Dec 1, 1996·Genetics·J GoudetF Rousset
May 1, 1997·Trends in Genetics : TIG·D L HartlA R Lohe
Nov 24, 1999·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·R Castiglia, E Capanna
Jan 26, 2000·Nature·J Britton-DavidianM da Luz Mathias
Jun 3, 2000·Genetics·J K PritchardP Donnelly
Jun 14, 2001·Trends in Ecology & Evolution·L H. Rieseberg
Mar 29, 2003·Genetics·Gregory A Wilson, Bruce Rannala
Apr 3, 2004·Evolution; International Journal of Organic Evolution·Thadsin PanithanarakJeremy B Searle
Oct 5, 2006·Evolution; International Journal of Organic Evolution·Patrick BassetJacques Hausser
Oct 1, 1994·Trends in Ecology & Evolution·C Moritz

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Citations

Aug 22, 2013·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Valeria MericoSilvia Garagna
Jul 28, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·Ma Assumpció Sans-FuentesMa José López-Fuster
Jul 24, 2014·Chromosoma·Silvia GaragnaJeremy B Searle
Feb 13, 2010·Evolution; International Journal of Organic Evolution·Paolo FranchiniRiccardo Castiglia
Dec 2, 2010·Retrovirology·Christine A Kozak
Nov 26, 2009·PLoS Genetics·Michael A WhiteBret A Payseur
Nov 13, 2008·Cytotechnology·Paola RebuzziniSilvia Garagna

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