Reproductive Long Intergenic Noncoding RNAs Exhibit Male Gamete Specificity and Polycomb Repressive Complex 2-Mediated Repression

Plant Physiology
Cameron JohnsonVenkatesan Sundaresan

Abstract

Long noncoding RNAs (lncRNAs) have been characterized extensively in animals and are involved in several processes, including homeobox gene expression and X-chromosome inactivation. In comparison, there has been much less detailed characterization of plant lncRNAs, and the number of distinct lncRNAs encoded in plant genomes and their regulation by developmental and epigenetic mechanisms remain largely unknown. Here, we analyzed transcriptome data from Asian rice (Oryza sativa) and identified 6,309 long intergenic noncoding RNAs (lincRNAs), focusing on their expression in reproductive tissues and organs. Most O. sativa lincRNAs were expressed in a highly tissue-specific manner, with an unexpectedly high fraction specifically expressed in male gametes. Mutation of a component of the Polycomb Repressive Complex2 (PRC2) resulted in derepression of another large class of lincRNAs, whose expression is correlated with H3K27 trimethylation in developing panicles. Overlap with the sperm cell-specific lincRNAs suggests that epigenetic repression of lincRNAs in the panicles was partially relieved in the male germline. Expression of a subset of lincRNAs also showed modulation by drought in reproductive tissues. Comparison with other cereal...Continue Reading

Citations

Jan 4, 2020·Genome Research·Chenxin LiJonathan I Gent
Jan 4, 2020·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Yue LuYu Zhao
Aug 9, 2020·Frontiers in Plant Science·Mohammad PourkheirandishMohan B Singh
Oct 21, 2020·Nucleic Acids Research·Jingjing JinPeijian Cao
Mar 26, 2021·Frontiers in Plant Science·Adil AbbasLiyong Cao

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