Reproductive, menstrual and menopausal factors: which are associated with bone mineral density in early postmenopausal women?

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
M J GraingeD J Hosking

Abstract

The associations between a number of reproductive and menopausal factors and bone mineral density (BMD) were studied in a sample of early postmenopausal women. The study included 580 women aged 45-61 years who completed a risk factor questionnaire containing sections on obstetric and menstrual history. BMD measurements were taken at the anteroposterior (AP) spine, greater trochanter, femoral neck, total radius and whole body, along with whole body bone mineral content (BMC). In analyses adjusting for key confounders, number of pregnancies was more strongly associated with increased BMD than number of live births at all sites (p<0.05 at femoral neck and total radius), and menstrual years was more strongly associated with increased BMD than years since menopause (p<0.05 at all sites). Hysterectomized women had a significantly higher adjusted mean BMD than non-hysterectomized women at all sites (AP spine: 0.999 g/cm2 vs 0.941 g/cm2, p<0.001), although there were no significant differences in BMD between hysterectomized women who had a bilateral oophorectomy and those whose ovaries were preserved. Negative associations between the duration of hot flushes and BMD were statistically significant (p<0.05) at the three non-hip sites. In...Continue Reading

Citations

May 20, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Hawley Almstedt Shoepe, Christine M Snow
Nov 13, 2010·Journal of Bone and Mineral Metabolism·Wojciech PluskiewiczBogna Drozdzowska
Mar 1, 2013·Health Care for Women International·Mürüvvet Başer, Sultan Taşci
Dec 15, 2010·Obstetrical & Gynecological Survey·Peter F SchnatzDavid M O'Sullivan
Mar 25, 2005·Acta Orthopaedica·Magnus K KarlssonCaroline Karlsson
Jan 1, 2008·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·R GuptaP Gupta
Feb 3, 2007·Fertility and Sterility·L Joseph MeltonAdil E Bharucha
Jun 17, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Magnus K KarlssonCaroline Karlsson
Oct 12, 2014·Journal of Bone and Mineral Metabolism·Eunju AhnBo Ha Kim
Jan 18, 2007·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Xiaojing WangJoseph M Zmuda
Sep 11, 2009·Clinical Endocrinology·Markus Herrmann, Markus J Seibel
Dec 1, 2006·Maturitas·Abdellah El MaghraouiMohamed Adnane Tazi
Apr 22, 2006·Contraception·Summer L MartinsAnna F Glasier
Jul 3, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Yasemin YumusakhuyluNecdet Suer
May 23, 2012·Molecular and Cellular Endocrinology·Chunyan He, Joanne M Murabito
Jun 22, 2012·Contraception·Carmine NappiCostantino Di Carlo
May 29, 2003·American Journal of Physical Anthropology·Antonietta M CerroniMarc D Grynpas
Jul 9, 2010·Menopause : the Journal of the North American Menopause Society·Peter F SchnatzDavid M O'Sullivan
Nov 20, 2013·The Journal of Clinical Endocrinology and Metabolism·Samantha E ParkerElizabeth E Hatch
May 19, 2005·The Journal of Clinical Endocrinology and Metabolism·Elizabeth A StreetenBraxton D Mitchell
Apr 30, 2017·Climacteric : the Journal of the International Menopause Society·N BigliaR E Nappi
Apr 14, 2006·Gan to kagaku ryoho. Cancer & chemotherapy·Shinichiro KameyamaHisataka Uchima

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