Reprogramming for cardiac regeneration

Global Cardiology Science & Practice
Christophe RaynaudMagdi Yacoub

Abstract

Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods for different reprogramming strategies, and their promises and future challenges before clinical entry, are all discussed here.

References

Mar 13, 1999·The Journal of Clinical Investigation·S MakinoS Ogawa
Feb 26, 2000·Science·J M Slack
Oct 29, 2000·Cell Adhesion and Communication·S KanekarW Carver
Feb 24, 2001·Lancet·P MenaschéJ P Marolleau
Aug 2, 2003·Circulation Research·Giedrius GaudesiusStephan Rohr
Aug 27, 2005·International Journal of Cardiology·Tingzhong WangAiqun Ma
Apr 18, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Troy A BaudinoThomas K Borg
Jul 25, 2006·Nature Methods·Tenneille E LudwigJames A Thomson
Nov 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·Paul GadueGordon M Keller
Nov 4, 2006·Pharmacology & Therapeutics·Sian E HardingJulia Gorelik
Apr 17, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Irit HuberLior Gepstein
May 30, 2007·Archives of Internal Medicine·Ahmed Abdel-LatifBuddhadeb Dawn
Jul 17, 2007·Progress in Cardiovascular Diseases·Lucio BarileEduardo Marbán
Sep 27, 2007·Molecular Therapy : the Journal of the American Society of Gene Therapy·David AndersonChris Denning
Nov 6, 2007·Journal of the American College of Cardiology·Oren CaspiLior Gepstein
Nov 22, 2007·Science·Junying YuJames A Thomson
Dec 7, 2007·Nature Biotechnology·Masato NakagawaShinya Yamanaka
Feb 22, 2008·Proceedings of the National Academy of Sciences of the United States of America·W E LowryK Plath
Oct 22, 2008·Nature Biotechnology·Trond AasenJuan Carlos Izpisúa Belmonte
Jan 9, 2009·Nature Reviews. Molecular Cell Biology·Sebastian J Arnold, Elizabeth J Robertson
Mar 21, 2009·Blood·Yuin-Han LohGeorge Q Daley
Apr 14, 2009·Nature Biotechnology·Robert L JudsonRobert Blelloch
Aug 4, 2009·Journal of Zhejiang University. Science. B·Mei-xiang XiangChun Gui
Aug 12, 2009·Nature·Teruhisa KawamuraJuan Carlos Izpisúa Belmonte
Aug 12, 2009·Nature·Han LiManuel Serrano

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Citations

Oct 25, 2017·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A E Espinosa De YcazaM D Jensen

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Methods Mentioned

BETA
flow cytometry
transfection
genetic modification
dissection
fluorescence-activated cell sorting
FACS
genetic modifications
targeted mutations

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