Requirement of upstream activation sequences for nitrogen catabolite repression of the allantoin system genes in Saccharomyces cerevisiae.

Molecular and Cellular Biology
T G CooperH S Yoo

Abstract

Synthesis of the transport systems and enzymes mediating uptake and catabolism of nitrogenous compounds is sensitive to nitrogen catabolite repression. In spite of the widespread occurrence of the control process, little is known about its mechanism. We have previously demonstrated that growth of cells on repressive nitrogen sources results in a dramatic decrease in the steady-state levels of mRNA encoded by the allantoin and arginine catabolic pathway genes and of the transport systems associated with allantoin metabolism. The present study identified the upstream activation sequences in the 5'-flanking regions of the allantoin system genes as the cis-acting sites through which nitrogen catabolite repression is exerted.

References

Apr 1, 1976·Journal of Bacteriology·J Bossinger, T G Cooper
Feb 1, 1975·Journal of Bacteriology·T G Cooper, R Sumrada
Mar 1, 1975·Journal of Bacteriology·R P Lawther, T G Cooper
Jan 1, 1975·Molecular & General Genetics : MGG·R P LawtherT G Cooper
Feb 1, 1989·Genes & Development·W F OdenwaldR A Lazzarini
Aug 1, 1987·Journal of Bacteriology·R RaiT G Cooper
Oct 1, 1987·Molecular and Cellular Biology·N F LueR D Kornberg
Jun 1, 1974·Journal of Bacteriology·J BossingerT G Cooper
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·T G Cooper, R P Lawther
Dec 1, 1982·Molecular and Cellular Biology·R A Sumrada, T G Cooper

❮ Previous
Next ❯

Citations

Oct 30, 2016·Yeast·Ahu Karademir Andersson, Marita Cohn
Dec 1, 1991·Yeast·R G Buckholz, T G Cooper
Mar 4, 2000·The Journal of Biological Chemistry·S ScottT G Cooper
Jan 21, 2000·FEMS Microbiology Reviews·E G ter SchureC T Verrips
Mar 14, 1997·Biochimica Et Biophysica Acta·J Horák

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.