Requirements for quality of life instruments in clinical research

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Lynda C DowardHanne Thorsen

Abstract

The ability to produce high quality instruments for the assessment of quality of life has advanced considerably in recent years. As the science progresses it has become clear that certain standards must be met if outcome measures are to be capable of providing useful, reliable, and valid information within the context of clinical studies and trials. This paper specifies what these standards are with particular reference to theoretical basis, practicality, acceptability to respondents, unidimensionality, scaling and psychometric properties, and cultural validity and equivalence. The paper also indicates how failure to achieve such standards results in measures that are inaccurate and insensitive to true changes in outcome.

References

Jul 18, 1992·BMJ : British Medical Journal·J E BrazierL Westlake
May 1, 1992·Medical Care·D R NerenzD M Kahkonen
Aug 24, 1994·JAMA : the Journal of the American Medical Association·T M Gill, A R Feinstein
Dec 1, 1993·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·R BerzonS A Shumaker
Nov 17, 1998·Journal of Clinical Epidemiology·S FukuharaK Kurokawa
Sep 5, 1992·Health Policy·S M Hunt, S P McKenna

❮ Previous
Next ❯

Citations

Aug 4, 2011·Respirology : Official Journal of the Asian Pacific Society of Respirology·Louise GandertonEli Gabbay
Nov 27, 2008·Scandinavian Journal of Primary Health Care·John Brodersen, Hanne Thorsen
Apr 1, 2005·Expert Review of Pharmacoeconomics & Outcomes Research·Peter Hagell
Nov 20, 2012·The Knee·Jonathan D CominsJohn Brodersen
Jan 18, 2006·Acta Neurologica Scandinavica·M-Y KimP Hagell
May 21, 2013·Scandinavian Journal of Medicine & Science in Sports·J D CominsJ Brodersen
Nov 11, 2009·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Peter HagellPer Nyberg
Jul 25, 2007·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·John BrodersenSvend Kreiner
Jun 27, 2009·Multiple Sclerosis : Clinical and Laboratory Research·L C DowardB J Eckert
Jul 1, 2009·Therapeutic Advances in Neurological Disorders·Peter Hagell, Maria H Nilsson
Feb 24, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Jeanette WilburnSimon Campbell
May 25, 2006·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Peter Hagell, Albert Westergren
Jan 28, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Fatemeh Nasiri-AmiriReza Ali Mohammadpour
Nov 5, 2020·Scandinavian Journal of Medicine & Science in Sports·Jonathan D CominsMichael R Krogsgaard
Apr 18, 2021·The British Journal of Dermatology·Y T AbdelrazikA Y Finlay
Nov 4, 2020·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·L WoythalS Brorson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Lynda C Doward, Stephen P McKenna
Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Angelo Swaine-VerdierStephen P McKenna
Journal of Psychosomatic Research
András P KeszeiDavid L Streiner
© 2021 Meta ULC. All rights reserved