Requirements for screening and confirmatory methods for the detection and quantification of marine biotoxins in end-product and official control

Analytical and Bioanalytical Chemistry
Philipp Hess

Abstract

An overview is given of the biological origin of phycotoxins, as well as their chemical characteristics. Major poisoning types are described and examples of poisoning events are given to illustrate the importance of the phenomenon to both shellfish consumers and the shellfish producing industry. The characteristics of phycotoxins as natural products, the lack of predictability of their occurrence, economic drivers and the freshness of shellfish consumed in many countries result in a number of requirements for methods to be used in the efficient detection of these compounds. Subsequently, the performance of mouse bioassays and mass spectrometry as detection tools are compared for examples from Irish and French monitoring programmes to assess the usefulness of qualitative and quantitative tools in official control, and their fitness for purpose compared with the requirements. The final part of the paper critically reviews methods available for the end-product and official control of shellfish toxins and their use in screening and confirmatory approaches in monitoring. Recent expert consultations on the methodology for phycotoxins at European and global level are summarised and recommendations are made for future progress in this ...Continue Reading

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Citations

Feb 25, 2011·Analytical and Bioanalytical Chemistry·Pearl BlayJeremy E Melanson
Jul 21, 2011·Analytical and Bioanalytical Chemistry·Rudolf KrskaDon Forsyth
Feb 15, 2012·Journal of Agricultural and Food Chemistry·Jane KilcoyneChristopher O Miles
Mar 20, 2012·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Carlos GarciaNéstor Lagos
Sep 24, 2014·Analytical and Bioanalytical Chemistry·Katrina CampbellChristopher T Elliott
Aug 12, 2014·Toxicon : Official Journal of the International Society on Toxinology·Ernesto García-MendozaJosé Luis Peña-Manjarrez
Feb 24, 2016·Journal of Natural Products·Silas Anselm RasmussenThomas Ostenfeld Larsen
Dec 23, 2015·Journal of the Marine Biological Association of the United Kingdom·Elisa BerdaletHenrik Enevoldsen
Mar 24, 2011·Toxicon : Official Journal of the International Society on Toxinology·John A B AasenTore Aune
Aug 31, 2010·Toxicon : Official Journal of the International Society on Toxinology·John A B AasenTore Aune
Oct 13, 2015·Toxicon : Official Journal of the International Society on Toxinology·Simone BacchiocchiRoberta Orletti
May 25, 2015·Toxicon : Official Journal of the International Society on Toxinology·Andrew D Turner, Alejandra B Goya
Jul 5, 2016·Toxicon : Official Journal of the International Society on Toxinology·Keith HarrisonAndrew D Turner
May 29, 2014·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Lancelot MaphosaDiane E Mather
Jun 25, 2014·Food Science and Technology International = Ciencia Y Tecnología De Los Alimentos Internacional·F BianchiK Sivieri
Oct 16, 2014·Plant Foods for Human Nutrition·Fernanda Salamoni BeckerEduardo Valério de Barros Vilas Boas
Feb 20, 2021·Journal of Invertebrate Pathology·Andrew D TurnerBenjamin H Maskrey

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