Rescue Adjuvant Vaginal Progesterone May Improve Outcomes in Cervical Cerclage Failure

Geburtshilfe und Frauenheilkunde
Alina R RomanPenelope M Sheehan

Abstract

Introduction Aim of the study was to evaluate the effect of rescue adjuvant vaginal progesterone in women with ongoing, transvaginal ultrasound (TVUS)-confirmed cervical shortening despite cervical cerclage. Materials and Methods A retrospective case control study was performed of women undergoing cervical surveillance following either history- or ultrasound-indicated cervical cerclage. We compared women managed with cervical cerclage and vaginal progesterone to women managed with cervical cerclage alone. Women with a singleton pregnancy who underwent cervical cerclage were identified from a database. Data on the concurrent use of vaginal progesterone, cervical length measurements, interventions and birth outcomes were collected from patient notes and clinical pathology notes. Patients from each intervention group were matched, based on exact shortest cervical length measurements obtained during surveillance and age of gestation when the measurement was obtained. Results 66 women were matched and included in the study, based on exact shortest cervical length measurements. Each group had an identical mean shortest cervical length of 12.09 mm. The outcomes of 33 women who received both cervical cerclage and vaginal progesterone w...Continue Reading

Citations

Apr 29, 2020·American Journal of Perinatology·Rupsa C BoeligAmanda Roman
Aug 14, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Pauric O'ReillySiobhan Corcoran

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