PMID: 26822051Jan 30, 2016Paper

Research advances of anti-tumor immune response induced by pulse electric field ablation

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Cui Guang-Ying, Diao Hong-Yan

Abstract

As a novel tumor therapy, pulse electric field has shown a clinical perspective. This paper reviews the characteristics of tumor ablation by microsecond pulse and nanosecond pulse electric field, and the research advances of anti-tumor immune response induced by pulse electric field ablation. Recent researches indicate that the pulse electric field not only leads to a complete ablation of local tumor, but also stimulates a protective immune response, thereby inhibiting tumor recurrence and metastasis. These unique advantages will show an extensive clinical application in the future. However, the mechanism of anti-tumor immune response and the development of related tumor vaccine need further studies.

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