PMID: 26350017Sep 10, 2015Paper

Research advances on prenatal maternal serum markers for screening adverse pregnancy outcomes

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Qin-qin Shen, Tan Zhang

Abstract

The routine prenatal maternal serum testing is widely used for screening of birth defects, including Down syndrome, trisomy 18 syndrome and neural tube defects. The testing results are also associated with other adverse pregnant outcomes such as fetal surface structural abnormalities, gestational hypertension disease, intrahepatic cholestasis of pregnancy, premature rupture of membranes, abortion, stillbirth, intrauterine growth restriction and macrosomia; therefore the abnormal levels of serum markers might be used for predicting these adverse pregnant outcomes.

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