PMID: 7495473Sep 1, 1995Paper

Research on antibacterial and antifungal agents. XII--Synthesis and antimicrobial activity of some Mannich bases of diarylpyrroles

Il Farmaco
G C PorrettaN Simonetti

Abstract

The synthesis and antimicrobial activity of some Mannich bases of diarylpyrroles are reported. The obtained data show that activity is closely connected to molecular basicity. Results are discussed on the basis of structure activity relationships.

Related Concepts

Microbicides
Antibiotics
Antibiotics, Antifungal
Candida albicans
Gram-Negative Bacteria
Gram-Positive Bacteria
Fungus Drug Sensitivity Tests
In Vivo NMR Spectroscopy
Pyrroles
Structure-Activity Relationship

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